Eradication Pseudomonas aeruginosa infection in a 19-year-old boy with cystic fibrosis, bronhiectasis and pneumotorax
INTRODUCTION: Colonization with Pseudomonas aeruginosa (PA) is common in older kids with cystic fibrosis (CF) and there is increasing evidence that transmissible strains may cross-colonise patients. PA colonization is usually difficult to eradicate with antimicrobial therapy and, in some children and younger patients, infection is associated with rapid decline in pulmonary function and increased hospitalization. Diffuse bronchiectasis is seen in patients with cystic fibrosis. CASE REPORT: A 19-year-old male with CF severe lungs disease and liver insufficiency presented with coughing and breathing difficulties with wheezing progressed to generalized bad situations and Pseudomonas aerigenosa opportunic suprainfection. The effect of combined three antibiotics therapy was very successful as eradication of Pseudomonas aerigenosa. Lung physiological tests were pathologically changed with obstructive and restrictive reductions of vital pulmonal parameters. DISCUSSION: Cystic fibrosis (CF) is the most common potentially lethal genetic disease in the white population. Improvements in life expectancy have led to an increased recognition of lungs and hepatobiliary-pancreatic CF complications. CONCLUSIONS: Cystic fibrosis is a genetic disease usually diagnosed by abnormal sweat testing. Despite the best efforts by CF clinic pediatricians, patients with CF eventually reach the point of respiratory insufficiency, and lungs can no longer sustain, and patients need lungs transplantation.