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Background: Medical professionals (doctors and other medical staff) in the field of healthcare everyday must make calculated decisions which have important consequences, impacting patients on the individual level, local (community), national or global level. Healthcare professionals must at times make these choices with limited information, resources, and knowledge, and yet is is expected that these decisions are highly calculated and accurate. It is important to familiarise oneself with the exact definitions regarding medical decision making. Objective: The aim of this study was to describe application of the most important rules to help decision makers to be good or excellent decision makers in medical practice at every level of health care system. Methods: The author used descriptive method of explanation teoretical and practical issues regarding application of od decision making processes in the praxis, based on searchied scientific literature about this topic deposited in online databases. Results and Discussion: The author of this paper discussed about important topics: a) the importance of medical decision in emergency situations; b) the varies of decision making with solving problems by medical professionals; c) the limitations when it comes to medical decison making; and d) what doctors need to follow regarding decision making in the praxis. Two factors that have influenced to the decision process: a) degree of uncertainty about future events; b) usefulness of outcomes in any particular case. The clinical decision problem analysis process demands: a) explicit formalization of a decision making problem or the description of the medical problem decision with a registration of all possible actions which have to be undertaken and registration of all the possible so determined outcomes. b) construction of the decision tree which presents all described actions and outcomes with predictions of the probabilities and the choice of the most optimal action based on the probability outcome and its use. Doing this allows us to delve deeper into more intricate options present within medical decision making. Simple put, a decision is a choice between two options. The person or entity conducting that decision is the decision maker. The exact definition is “Under the decision should imply some specific action which is selected from several variables or which satisfies the expectation that is previously set”.Many different factors and individuals may be involved in medical decision making, with varying consequences, according to different players and settings. Conclusion: A vital component of medical decision making is evaluation. Decision makers must concisely evaluate situations, in order to make better choices. For example, when examining a health care system, their decisions should consider the following questions, such as, what is the health status of the given population? What economic resources are at the disposal of our patients, and government? How effective is the current healthcare model that is already in place? Does the existing social system pay enough attention to the healthcare protection? Does the organisation structure of the healthcare system satisfy? Are the existing practice and the healthcare technologies secure, effective, and suitable? Are the planning, programming, determination and the choice of priority the adequate to the needs of people? How are the monitoring and evaluation of healthcare system quality organised? These are a few examples of evaluation in medical decision making.

Acta Informatica Medica journal (www.actainformmed.org), as Biomedical Informatics journal, during past 30 years of existing played important role in distribution of knowledge and experience within this scientific field, by publishing contributions of the biomedical experts from worlwide and spreading of Biomedical informatics knowledge and experiences in scientific and academic community. Acta Informatica Medica journal has been founded in the year 1993 as official journal of Bosnian-Herzegovinan Society of Medical Informatics (BHSMI). In the year 2019 Acta Informatica Medica has been accepted as official journal of the European Federation for Medical Informatics (www.efmi.org), besides 3 other journals: International Journal of Medical Informatics, Methods of Information in Medicine and European Journal of Biomedical Informatics. Journal Acta Informatica Medica is abstracted and indexed in 30 on-line data bases, including Pubmed, Pubmed Central, Scopus, Embase, Hinari, etc. The journal follows the Guidelines and recommendations of ICJME, COPE, EASE, WAME, etc. as well as the recommendations of the “Sarajevo Declaration on Integrity and Visibility of Scholarly Journals”, accepted by 17 Editors of biomedical journals at “SWEP 2018” Conference held in Sarajevo and printed in the countries in South-Eastern Europe. SCImago rank for 2021 announced the bibliometric list of the journals deposited in SCOPUS indexed database. On the list are 16 journals which are published in Bosnia and Herzegovina, and between them are 7 within biomedical sciences. Three highest are Bosnian Journal of Basic Medical Sciences - H-Index is 29, Medical Archives - H-Index is 26 and Acta Informatica Medica - H-Index is 24, etc. Acta Informatica Medical journal has Impact Score, Overall Ranking, h-index, SJR, Rating, Publisher updated on May 27, 2022: Impact Score - 1.87; h-Index - 24; Rank -12749 and SJR - 0.372.

Background: Scientometry is a part of Scientology (the science of science) that analyzes scientific articles and their citation in a selected sample of scientific journals. The basic part of scientometry is bibliometrics, which was introduced in the 1970s to mark quantitative research on communication processes by applying appropriate mathematical and statistical methods to published publications. Scientific research is the only real way and method for the proliferation of true knowledge in all spheres of science, but also in academic institutions. The ability to study a scientific problem is the highest level of knowledge. Medical

I. Masic, N. Naser, A. Kapetanovic, N. Salihefendic, M. Zildžić

Background: We could say that traditional healing is a way of healing that has been common since ancient times. It has been passed down from generation to generation for many centuries. Magic medicine, although not approved by any of the monotheistic religions present in Bosnia and Herzegovina, and strictly prohibited by Islam, in the form of various magical acts and spells, exists among the people. Some of these magical practices have their roots in the pre-Christian Slavic period and earlier. Objective: The aim of this article was to provide the review of the traditional medicine during the history and today in Bosnia and Herzegovina. Methods: Review of the available literature, personal contacts and personal experience in contact with the traditional medcine. Discussion: Some of these magical practices have their roots in the pre-Christian Slavic period and earlier. Since the cause of the disease was usually associated with evil beings of supernatural powers, a deity or God’s will or punishment, it is understandable that priests have long been engaged in healing. Especially in the mentally ill, there seemed to be a certain divine or demonic origin of the disease. Muslim folk medicine divides diseases into two groups; in fevers and obsessions with unclean spirits. Folk medicine knows the healing properties of herbs and other substances of animal or mineral origin. The medicinal properties of simple foods that can be found in every home are also widely used, such as: milk, honey, vinegar, oil, onion, and garlic. Prescription books, known as “ljekaruše”, were created by collecting and writing down folk remedies. They were written mostly by Catholic priests. “Witch doctors” or “healers” have been preserved in Orthodox monasteries. Conclusion: Traditional medicine is important for history of medicine, ethnology, anthropology, and abounds in folklore elements. It is an area that leads to knowing, understanding or feeling the very nucleus of a nation.

Acta Informatica Medica journal (www.actainformmed.org), as Biomedical Informatics journal, during past 30 years of existing played important role in distribution of knowledge and experience within this scientific field, by publishing contributions of the biomedical experts from worlwide and spreading of Biomedical informatics knowledge and experiences in scientific and academic community. Acta Informatica Medica journal has been founded in the year 1993 by Izet Masic and Zoran Ridjanovic, as official journal of Bosnian-Herzegovinan Society of Medical Informatics (BHSMI). In the year 2019 Acta Informatica Medica has been accepted as official journal of the European Federation for Medical Informatics (www.efmi.org), besides 3 other journals: International Journal of Medical Informatics, Methods of Information in Medicine and European Journal of Biomedical Informatics. Journal Acta Informatica Medica is abstracted and indexed in 30 on-line data bases, including Pubmed, Pubmed Central, Scopus, Embase, Hinari, etc. The journal follows the Guidelines and recommendations of ICJME, COPE, EASE, WAME, etc. as well as the recommendations of the “Sarajevo Declaration on Integrity and Visibility of Scholarly Journals”, accepted by 17 Editors of biomedical journals at “SWEP 2018” Conference held in Sarajevo and printed in the countries in South-Eastern Europe. The journal supports presentations at conferences held in Bosnia and Herzegovina. The abstract papers presented at “The Mediterranean Seminar on Science Writing, Editing and Publishing“ – “SWEP 2016”, “SWEP 2018”; “SWEP 2020” and “SWEP 2021”, also found its place in the journal, by which we met our goal of promoting science and scientific publication at the area of Bosnia and Herzegovina and other countries in the region. Acta Informatica Medica has been ranked: Highest Impact Factor for 2011–2022 was 1.496 and Lowest Impact Factor for 2011–2022 was 0.59. During the year 2021 in Acta Informatica Medica journal was published 46 papers. From total amount published papers, 67,39% was original papers, where it was more published original papers in the journal than in the year 2020. Acta Informatica Medica has value of important metrics (last updated on November 16, 2021): Impact Score - 1.50, h-Index - 20, Rank - 15980, SJR - 0.267.

R. A. Ghayda, Keumwha Lee, Y. Han, Seohyun Ryu, Sung Hwi Hong, Sojung Yoon, G. H. Jeong, Jae-Won Yang et al.

The aim of this study is to provide a more accurate representation of COVID‐19's case fatality rate (CFR) by performing meta‐analyses by continents and income, and by comparing the result with pooled estimates. We used multiple worldwide data sources on COVID‐19 for every country reporting COVID‐19 cases. On the basis of data, we performed random and fixed meta‐analyses for CFR of COVID‐19 by continents and income according to each individual calendar date. CFR was estimated based on the different geographical regions and levels of income using three models: pooled estimates, fixed‐ and random‐model. In Asia, all three types of CFR initially remained approximately between 2.0% and 3.0%. In the case of pooled estimates and the fixed model results, CFR increased to 4.0%, by then gradually decreasing, while in the case of random‐model, CFR remained under 2.0%. Similarly, in Europe, initially, the two types of CFR peaked at 9.0% and 10.0%, respectively. The random‐model results showed an increase near 5.0%. In high‐income countries, pooled estimates and fixed‐model showed gradually increasing trends with a final pooled estimates and random‐model reached about 8.0% and 4.0%, respectively. In middle‐income, the pooled estimates and fixed‐model have gradually increased reaching up to 4.5%. in low‐income countries, CFRs remained similar between 1.5% and 3.0%. Our study emphasizes that COVID‐19 CFR is not a fixed or static value. Rather, it is a dynamic estimate that changes with time, population, socioeconomic factors, and the mitigatory efforts of individual countries.

A. Skrbo, I. Masic, T. Čatić, A. Šukalo

Background: For many years, pharmacy and medicine were inseparable sciences, so everything that was done in the field of medicine, that is, treatment, can be related to pharmacy. The history of pharmacy therefore also includes the history of medicine, at least until the 13th century, when pharmacy was officially separated from medicine. Objective: The aim of this study was: to describe the books and monographs that are available on the Internet, which deal with the study of the history of Pharmacy; and to show pharmaceutical history museums around the world and their unique collections of pharmaceutical artifacts. Methods: During the preparation of this paper, a descriptive method of analysis from the available literature was used. The analysis of available literature included professional books, monographs, articles and other literature available on online browsers. Results and Discussion: Today there are a large number of societies, academies, associations and foundations dealing with the history of pharmacy. Also, a lot of books, monographs and scientific papers published in on-line databases. The goal of each organization is the research of historical facts in the field of pharmacy and medicine that will be shared with professionals, but also persons who are not from the profession (doctors, librarians, archaeologists, archivists). A large number of museums have been opened for the history of pharmacy, and almost every developed country has such a museum. Such museums represent a national treasure, because they preserve the valuables of pharmacy from the territory of the country, as well as the world.

Background: The rich history of pharmacy in Bosnia and Herzegovina has been sporadically dealt with systematically, except by enthusiasts and researchers. The only book on this topic was published in 1958, and after the aggression against Bosnia and Herzegovina, the history of pharmacy was treated mainly as part of the history of medicine. The lack of a culture of memory and a systematic approach to historical heritage brought together a group of experts who deal with this topic in more detail and collect available historical relevant material. Pharmacy as a highly regulated health discipline also in Bosnia and Herzegovina is a legacy of legal acts and documents that depict different periods and the development of pharmacy itself under the influence of circumstances and legislation. Objective: The aim of this paper is to show the development of legislation related to the pharmaceutical sector in Bosnia and Herzegovina through the historical periods of its development. Methods: This is retrospective research based on internet sources, archives and publications available in libraries. Results and Discussion: The available legal regulations and documents through five periods of pharmaceutical development were analysed, from which it can be concluded that the organization of the pharmaceutical industry and its development over time remained stricter. Legal regulations depict the role of pharmacy in the health system, but they also represent sources for further research in this area, and constitute important historiographical material. The analysis of legal regulations speaks volumes about the way pharmaceutical activity is organized, so it is possible to follow the appearance of the first pharmacies, pharmacists, requirements for the quality of medicines, production and the modern role of pharmacists in the health system. Pharmaceutical legislation will certainly be the subject of future negotiations on the accession of Bosnia and Herzegovina to the European Union, and harmonization with the acquis of the EU is expected in the coming period.

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