In this paper, we analyze examples of research institutes that stand out in scientific excellence and social impact. We define key practices for evaluating research results, economic conditions, and the selection of specific research topics. Special focus is placed on small countries and the field of artificial intelligence. The aim is to identify components that enable institutes to achieve a high level of innovation, self-sustainability, and social benefits.

The flavor puzzles remain among the most compelling open questions in particle physics. The striking hierarchies observed in the masses and mixing of charged fermions define the Standard Model (SM) flavor puzzle, a profound structural enigma pointing to physics beyond the SM. Simultaneously, the absence of deviations from SM predictions in precision measurements of flavor-changing neutral currents imposes severe constraints on new physics at the TeV scale, giving rise to the new physics flavor puzzle. This review provides an overview of a selection of recent advancements in flavor model building, with a particular focus on attempts to address one or both of these puzzles within the quark sector.

The flavor puzzles remain among the most compelling open questions in particle physics. The striking hierarchies observed in the masses and mixing of charged fermions define the Standard Model (SM) flavor puzzle, a profound structural enigma pointing to physics beyond the SM. Simultaneously, the absence of deviations from SM predictions in precision measurements of flavor-changing neutral currents imposes severe constraints on new physics at the TeV scale, giving rise to the new physics flavor puzzle. This review provides an overview of a selection of recent advancements in flavor model building, with a particular focus on attempts to address one or both of these puzzles within the quark sector.

Leveraging recent advancements in machine learning-based flavor tagging, we develop an optimal analysis for measuring the hadronic cross-section ratios R_bRb, R_cRc, and R_sRs at the FCC-ee during its WWWW, ZhZh, and t\bar{t}tt‾ runs. Our results indicate up to a two-order-of-magnitude improvement in precision, providing an unprecedented test of the SM. Using these observables, along with R_\ellRℓ and R_tRt, we project sensitivity to flavor non-universal four-fermion (4F) interactions within the SMEFT, contributing both at the tree-level and through the renormalization group (RG). We highlight a subtle complementarity with RG-induced effects at the FCC-ee’s ZZ-pole. Our analysis demonstrates significant improvements over the current LEP-II and LHC bounds in probing flavor-conserving 4F operators involving heavy quark flavors and all lepton flavors. As an application, we explore simplified models addressing current BB-meson anomalies, demonstrating that FCC-ee can effectively probe the relevant parameter space. Finally, we design optimized search strategies for quark flavor-violating 4F interactions.

The Froggatt-Nielsen (FN) mechanism, a prominent framework for explaining the observed flavor hierarchies, generically predicts the existence of an axion-like particle (ALP). This work examines a class of FN models based on ℤN discrete symmetries. We chart the allowed parameter space from a set of theoretical considerations and construct explicit renormalizable completions with minimal field content necessary to generate consistent textures. We then conduct comprehensive phenomenological analyses of two particularly elegant ℤ4 and ℤ8 models, highlighting the interplay between the effects of the ALP and the associated UV fields. We find that the FN scale can be as low as a few TeV.

In our recent attempt to explain flavor hierarchies [1], a gauged SU(2) flavor symmetry acting on left-handed fermions provides a ground to introduce three independent rank-one contributions to the Yukawa matrices: a renormalizable one for the third family, a mass-suppressed one for the second family, and an additional loop-suppressed factor for the first family. Here, we demonstrate how minimal quark-lepton unification à la Pati-Salam, relating down-quarks to charged leptons, can significantly improve this mechanism. We construct and thoroughly analyze a renormalizable model, performing a comprehensive one-loop matching calculation that reveals how all flavor hierarchies emerge from a single ratio of two scales. The first signatures may appear in the upcoming charged lepton flavor violation experiments.

Flavor deconstruction refers to non-universal gauge extensions where the original gauge symmetry is deconstructed into separate copies, one for each family. A hierarchical chain of symmetry breaking provides an attractive low-scale solution to the flavor puzzle, consistent with flavor-changing neutral currents and finite naturalness. Although successful in explaining the origin of flavor hierarchies in the quark and charged lepton sectors, existing models have struggled with the large and seemingly anarchic mixing observed in neutrino oscillations. This letter identifies conditions under which neutrino anarchy may arise from flavor deconstruction in generic models with right-handed neutrinos. When deconstruction is applied to carefully chosen subgroups of the extended gauge symmetry, hierarchies in the seesaw formula cancel out.

We propose a unique topological portal between quantum chromodynamics (QCD) and a dark sector characterized by a global symmetry breaking, which connects three QCD to two dark pions. When gauged, it serves as the leading portal between the two sectors, providing an elegant, self-consistent scenario of light thermal inelastic dark matter. The inherent antisymmetrization leads to diminished annihilations at later times and suppressed direct detection. However, novel collider signatures offer tremendous prospects for discovery at Belle II.

The stability of the electroweak scale, challenged by the absence of deviations in flavor physics, prompts the consideration of SMEFT scenarios governed by approximate SM flavor symmetries. This study examines microscopic theories that match onto a set of $U(3)^5$-symmetric dimension-6 operators. Renormalization group mixing from the ultraviolet to the electroweak scale yields significant phenomenological constraints, particularly pronounced for UV-motivated directions. To demonstrate this, we explore a complete suite of tree-level models featuring new spin-0, 1/2, and 1 fields, categorized by their irreducible representations under the flavor group. We find that for the leading directions, corresponding to a single-mediator dominance, RG mixing effects occasionally serve as the primary indirect probe.

We posit that the distinct patterns observed in fermion masses and mixings are due to a minimally broken U(2)_{q+e} flavor symmetry acting on left-handed quarks and right-handed charged leptons, giving rise to an accidental U(2)^{5} symmetry at the renormalizable level without imposing selection rules on the Weinberg operator. We show that the symmetry can be consistently gauged by explicit examples and comment on realizations in SU(5) unification. Via a model-independent analysis of a standard model viewed as an effective field theory, we find that selection rules due to U(2)_{q+e} enhance the importance of charged lepton flavor violation as a probe, where significant experimental progress is expected in the near future.

Exclusive semileptonic b hadron decays (b → uℓν) serve as a sandbox for probing strong and electroweak interactions and for extracting the CKM element Vub. Instead, this work investigates their underexplored potential to reveal new short-distance physics. Utilizing SMEFT as a conduit to chart territory beyond the SM, we demonstrate that substantive new physics contributions in b → uℓν are necessarily linked to correlated effects in rare neutral-current b decays, neutral B meson mixing or high-mass Drell-Yan tails. We find that measurements of the latter processes strongly restrict the allowed deviations in the former. A complete set of tree-level mediators, originating from a perturbative ultraviolet model and matching at dimension 6, is thoroughly explored to support this assertion. As a showcase application, we examine the feasibility of a new physics interpretation of the recent tension in exclusive |Vub| extraction from B → Vℓν where V = (ρ, ω).

We propose an economical model to address the mass hierarchies of quarks and charged leptons. The light generations of the left-handed fermions form doublets under an SU(2)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ \textrm{SU}(2) $$\end{document} flavor symmetry, which is gauged. The generational hierarchies emerge from three independent rank-one contributions to the Yukawa matrices: one is a renormalizable contribution, the second is suppressed by a mass ratio, and the last by an additional loop factor. The model is renormalizable, features only a handful of new fields, and is remarkably simple compared to typical completions of gauged flavor symmetries or Froggatt–Nielsen. The model has a rich phenomenology, and we highlight promising signatures, especially in the context of K and B meson physics. This includes an interpretation of the latest B+→K+νν¯\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$B^+ \rightarrow K^+ \nu \bar{\nu }$$\end{document} measurement from Belle II.

Exclusive semileptonic $b$ hadron decays ($b \to u \ell \nu$) serve as a sandbox for probing strong and electroweak interactions and for extracting the CKM element $V_{ub}$. Instead, this work investigates their underexplored potential to reveal new short-distance physics. Utilizing SMEFT as a conduit to chart territory beyond the SM, we demonstrate that substantive new physics contributions in $b \to u \ell \nu$ are necessarily linked to correlated effects in rare neutral-current $b$ decays, neutral $B$ meson mixing or high-mass Drell-Yan tails. We find that measurements of the latter processes strongly restrict the allowed deviations in the former. A complete set of tree-level mediators, originating from a perturbative ultraviolet model and matching at dimension 6, is thoroughly explored to support this assertion. As a showcase application, we examine the feasibility of a new physics interpretation of the recent tension in exclusive $|V_{ub}|$ extraction from $B \to V \ell \nu$ where $V=(\rho,\omega)$.

Short-distance new physics at (or slightly) above the TeV scale should not excessively violate the approximate flavor symmetries of the SM in order to comply with stringent constraints from flavor-changing neutral currents. In this respect, flavor symmetries provide an effective organizing principle for the vast parameter space of the SMEFT. In this work, we classify all possible irreducible representations under U(3)5 flavor symmetry of new heavy spin-0, 1/2, and 1 fields which integrate out to dimension-6 operators at the tree level. For a general perturbative UV model, the resulting flavor-symmetric interactions are very restrictive and, in most cases, predict a single Hermitian operator with a definite sign. These leading directions in the SMEFT space deserve particular attention. We derive an extensive set of present experimental constraints by utilizing the existing global SMEFT fits, which incorporate data from top quark, Higgs boson, and electroweak measurements, along with constraints on dilepton and 4-lepton contact interactions. The derived set of bounds comprehensively summarises the present knowledge from indirect searches of flavor-blind new physics mediators.