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Svjetlana Grgić

Društvene mreže:

Natasa Pejanovic-Skobic, Kristina Galic, Ilijana Kapcevic, S. Grgić, Marina Vasilj, Sandra Lakičević, Marija Bender, Tanja Zovko

Objective: The main objective of this research is to determine the prevalence and characteristics of neurological manifestations in hospitalized patients with SARS-CoV-2 infection. Methods: A cross-sectional study was conducted. 572 hospitalized patients at the COVID Department of Pulmonology of the Mostar University Clinical Hospital in the six-month period from October 31, 2020, to April 30, 2021, were included. We analyzed the incidence of neurological manifestations and the influence of comorbidities and metabolic syndrome on stroke incidence in COVID-19 patients. We analyzed hospital length of stay and mortality in patients with and without neurological manifestations. The research was conducted with respect to all the determinants of the Helsinki Declaration. Results: 572 patients, 351 men (61.4%), and 221 women (38.6%) were included. A fatal outcome was present in a quarter of patients (25.3%). Neurological manifestations were found in 163 patients (28.5%). Myalgia was the most common (16.1%). The following were reported: headache (9.6%), loss of taste (7.34%), loss of smell (6.8%), and vertigo (2.5%). There was a significant difference regarding loss of smell between males and females (p=0.04). The cerebrovascular incident was present in 2.97% of patients and was more frequent in the group of patients with metabolic syndrome. Patients with neurological manifestations had a longer hospital stay, but it was not statistically significant (p=0.9319). The presence of neurological manifestations in general did not influence the mortality rate. Conclusion: Patients with SARS-CoV-2 infection can present with neurologic findings such as myalgia, headache, loss of smell or taste, vertigo, as well as cerebrovascular incidents. Patients with neurological manifestations had longer hospital stays, but the presence of neurological manifestations in general did not influence the mortality rate.

M. Raguž, Katarina Šoljić, Željka Prce, V. Mikulić, T. Barišić, S. Grgić

Background : This study conducted at the Clinic for Children’s Diseases of the University Clinical Hospital Mostar, aims to highlight the characteristics, frequency, course, most common complications and treatment outcomes of pregnant women and their late preterm infants according to gestational age. Methods : This study is a retrospective epidemiologic study for the period from 1/1/2018 to 31/12/2021. The study included all the preterm infants who were born at a gestational age from 34 +0/7 to 36 +6/7 weeks and their mothers. Results : In the period under study, a total of 7178 infants were born, of which 253 (3.52%) were late preterm infants. The results show that most mothers were between 30 and 39 years of age, pregnant for the first time with a single pregnancy, delivered by caesarean section, with complications in 53.1% of the pregnancies. All the analyzed pathological conditions were more common in the pregnancies which ended at 34 weeks. Our results indicate that the late preterm babies had a good birth weight (53.8%) and high vitality scores (93%) at birth, but these scores were not confirmed on the first day of life. A significant number of late preterm infants had some pathological condition which was treated in the intensive care units (ICU) ( p < 0.001). Conclusions : The study concludes that half of the pregnant women had risk factors which were the basis for the preterm births and the development of complications in the late preterm infants. Furthermore, despite good birth weight and vitality scores at birth, only one fifth of the late preterm infants were not treated with medications or developed pathological conditions, whereas only one third required no intensive care treatment. It is, therefore, necessary to improve the monitoring and understanding of such pregnancies, implement antenatal corticosteroid therapy, and increase parental awareness to ensure long-term and frequent monitoring of late preterm infants by pediatricians.

M. Raguž, Jerko Brzica, S. Grgić, Vedran Bjelanović, A. Mustapić, Darinka Šumanović Glamuzina, M. Mabić

Background: The aim of this study was to show the frequency and epidemiological characteristics of pregnant women who tested positive for SARS-CoV-2 during childbirth as well as the course, mode and outcome of their newborn treatment and diet after discharge. The aim is also to show individual symptoms developed by newborn from pregnant women who test positive for SARS-CoV-2. Method: The study included all the infants born to the pregnant women who tested positive for SARS-CoV-2 on a PCR test 24 hours prior to delivery or, had already been confirmed positive for the infection and had developed symptoms of the virus or had started treatment for SARS-CoV-2 several days prior to delivery. Results: 43/3237 (1.32%) of the pregnant women tested positive for the SARS-CoV-2 virus or had been infected prior to admission and were positive during delivery. A total of 45 newborn infants were transferred to a special room for the care of newborn infants born to SARS-CoV-2-positive mothers at the Department of Neonatology. Specifically, 30/45 (66.7%) of the newborn infants developed symptoms within the first hours of birth which withdrew spontaneously within 24–48 hours after birth. The symptoms referred to are not specific forSARS-CoV-2 infection and are not particularly indicative of infection. Conclusions: The conclusion of this short 21-month study is that prenatal and postnatal duration and outcome in infants is not aggravated by pregnant women who tested positive for SARS-CoV-2. Despite the individual symptoms described above and the pathological states the children developed during hospitalization, all the newborn infants were discharged from hospital in full health, and they were all breastfeeding following discharge in conditions which respected all the epidemiological preventive measures.

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