Introduction: Postoperative Atrial Fibrillation (POAF) is associated with a higher rate of postoperative complications and mortality, as well as with longer hospitalization and increased treatment costs. We have designed and performed a randomized, trial of pharmacological prophylaxis in which the event of interest is POAF. Aim: The aim of this study is to reduce the risk of postoperative, complications associated with this arrhythmia. Methods: We included 240 stable patients with a coronary heart disease, who were referred to elective surgical revascularization of the myocardium. The patients were assigned into three groups of 80 patients each: group A (BB, beta blocker, comparator), group B (BB+ Amiodarone) and group C (BB + Rosuvastatin). The goal was to establish whether intervention by combination therapy was more useful than a comparator. Results: An event of interest (POAF) has occurred in 66 of the total 240 patients. Number of new POAF cases is the lowest in Group B, 14 (17.5%) compared to 25 (31.25%) new cases in the comparator group, and 27 new cases (33.75%) in group C. Absolute risk reduction was 13.75%, ≈14% less POAF in group B compared to comparator. Relative risk reduction was 56% (RR 0.56, p = 0.04). Number Needed to Treat was 7.27. In group C, 33.75% of patients developed POAF. Absolute risk was insignificantly higher in group C (2.5%, NS) compared to the comparator .The number needed to harm was high, 40. Conclusion: The results of our research show that prophylaxis of POAF with combined therapy BB + Amiodarone was the most efficient one.

Introduction: Glaucoma is the second leading cause of blindness in the world and represents a significant social and health problem. Early detection of glaucoma enables early initiation of treatment and may delay disease progression. The aim of this work is to determine whether it is possible to detect glaucoma in early stages. Methods: A public awareness campaign was carried out in University Clinic Center (UCC) in Tuzla, Bosnia and Herzegovina (B&H) during 2012, 2013, 2014 and 2015 Glaucoma Week, with one-day, free of charge screening of individuals. This screening program was composed of getting brief medical history, slit-lamp examination including intraocular pressure and anterior chamber dept evaluation and non-mydriatic fundus exam with evaluation of the cup/disk ration. Results: A total of 682 individuals were screened, 277 were male and 405 were female. The youngest individual was 8 years old and the oldest individual was 84 years old. The mean age was 57.6 years. Intraocular pressure higher then 21,9 mmHg was found in 83 patients. Conclusion: Glaucoma is a disease that affects visual acuity and gradually leads to blindness. It occurs in all age groups in both sexes and in all races. Early detection of disease and proper treatment can prevent permanent loss of vision. Detection and early treatment of glaucoma must become one of the leading public health programs in B&H.

Dear Editor, We read with interest article ‘‘Variation of Intraocular Pressure with Age and Gender’’ by Jeelani et al and we would like to highlight few facts. All intraocular pressure measurements as was stated in the article were carried on only in the sitting position during day, only once. Numbers of studies that measure night-time intraocular pressure in recumbent positions generally find higher mean IOPS. Articles of Liu et al showed that there is significant elevation of intraocular pressure during night. We believe that a material and methods in the article should have been written with more specific data. The authors should have mentioned if all IOP measurements were taken by same trained person or several trained. Also authors should have reported what were exclusion criteria for glaucoma. In our opinion the authors should have mentioned if the direct or indirect fundoscopies were performed. That way authors could have detected lesions due arterial hypertension or diabetes mellitus. In article of Sakata et al is written that IOP values increase progressively from the hypertensive patients without retinopathy, to the hypertensive with retinopathy and diabetic hypertensive with retinopathy. We would like to suggest authors to make a bigger sample and try to identify a relationship between intraocular pressure and systemic health parameters not only age and sex but also blood and obesity index. Apart of this we would like to suggest authors to try to include in next article also all patients older than 20 years. They could make then seven age groups, divided by decades ranging from 20 to 29 years to 80+years. Also interested study would be if the authors could investigate relationship between corneal diameter, central corneal curvature, central corneal thickness.