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Muhamed Kadić

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The paper semantically analyzes the corporeality in the poetic discourse of Momčilo Nastasijević. The verses indicate the semantic structure of the body through its sensuous, affective and ontological segment. The conceptual distinction between the body and corporeality is emphasized, by pointing to the body as a conceptual domain that is conceptualized through the plant world and corporeality as a quality that arises in bodily intercommunication. Corporeality is semantically formed in the fusion of bodily relationship and the dynamics of its meaning finds the words whose semantic content is dynamic, and in most cases these words are lexemes that denote processes in the vegetative world. Corporeality is not limited to the material appearance of the body, but is recognized as a space in which the body exists incorporeal and immaterial. Corporeality arises in the human physical-physiological substance of the body, but at the same time it is in the human being an inseparable form with the soul (feelings). There is an ontological component of meaning of the corporeality based on Christian ethical theses. Corporeality is also a metaphysical presupposition of human existence. It is confirmed in the songs with verses about the insatiability of thirst, i.e., eros, which is not bare libido sexualis, but longing and necessity for another being, i.e., the necessity to know the spiritual and divine principle through another body (another being). The function of desire is also shown in conceptual representations of corporeality. According to the poet's essays, desire is the disharmonization of the human personality, and that connotation predetermines the negative meaning of corporeality. In that sense, the body is a state of death and carries the potential for perversion. Hence, the thought of bodily renunciation and prohibition of bodily desire appears in the verses, which is also the influence of Christian views on Nastasijević's poetics and semantics of corporality.

The mammary glands of primigravid Wistar rats were investigated by stereological analysis in conditions of lead acetate administration via drinking water. The experiment was made in early summer period when absorbing ability of rat intestinum for lead is highest. Morphological state of glands was observed on 7th, 14th and 21st day of pregnancy. Groups of control animals were drinking deionized water but groups of experimental animals were drinking deionized water with added lead acetate. On paraffin sections coloured by HE method, volume density (VV) of glands structural elements were determined by multipurpose test system M42. Stereological analysis shows that lead diminishes the proliferative capacity of the mammary parenchyma and changes the morphofunctional differentiation of the overall structure in mammary gland during pregnancy. At the same time lead modifies quantitative trait of the mammary gland, i.e. the composition of the volume units in organ, without changing intramammary syncornization between the epithelium and lipocytes.

The present study was undertaken to investigate the changes in composition of the mammary gland volume unit through all phases of lactation in rats subjected to lead acetate administration via drinking water during the first pregnancy and lactation. Stereological analysis was performed on serial slices of the organs. The point of support for our study was the fact that lead, apart from being a poison of wide range, is mostly poisonous for gonads and to their supervisory neuroendocrine structures and the mammary gland, in morpho-functional sense, should be admitted as their integral part. On the 7th day of lactation there was significant difference of the alveolar and ductal epithelium phase, which was significantly reduced in animals treated by lead. In the same animals there were larger lumens of the alveoli and ducti, more abundant connective tissue and greater number of the adipocytes but these differences in comparison to control group were not significant. On the 14th day of lactation there was significantly greater presence of the adipocytes phase and stromal tissue while the volume of the epithelium of alveoli and ducti was significantly reduced in study group. There was also an increase of the alveoloductal lumen phase but this was not significant. On the 21st day of lactation there were significant difference in epithelial and stromal tissue phases in two groups, having a significant decrease in the epithelium, and significant increase of stromal tissue in glands of lactating rats treated by lead acetate. There were non-significant differences as far as the presence of the adipocytes and alveoloductal lumen volume were concerned although the values for both phases in study group were above the control values. On the basis of given results we concluded that lead changes the quantitative characteristics of the mammary gland, i.e. the composition of the volume unit of the organ through all phases of lactation.

The mammary mast cells number, distribution, type and some other structural characteristics was studied at 7., 14. and 21. postpartum date in lactating Wistar rats receiving deionized water of lead acetate via drinking water during the first lactation. Toluidine blue or alcian blue and safranine staining of the material from left abdominal mammary glands were used for histological, histochemical and morphometry evaluation. Thirty random immersion fields of three distant tissue section in the stromal compartment of each gland's areas were counted. The fluctuation of mammary mast cells number with peak at 14th postpartum date and dominance of granulated and with epithelium unassociated mast cells was estimated in normal lactating animals. The parallel progress of safranine-positive granules and secretory activity of mammary mast cells with the length of lactation was observed in the same group of animals. The fluctuation of mammary mast cells number during the lactational period with significant increased at 14th postpartum date and dominance with epithelium associated cells at the same time was estimated in lead acetate treated lactating animals. Safranine-stained positive material was dominant in mammary mast cells under the influence of lead. In the same group of animals the progression of release the secretory granules from mast cells and partial to total degranulation of cells was observed. During the lactation and under the influence of lead the mammary mast cells are associated with the gland changes in morphology and function.

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