Object tracking is one of the fundamental tasks in computer vision. It is used almost everywhere: human-computer interaction, video surveillance, medical treatments, robotics, smart cars, etc. Many object tracking methods have been published in recent scientific publications. However, many questions still remain unanswered, such as, which object tracking method to choose for a particular application considering some specific characteristics of video content or which method will perform the best (quality-wise) and which one will have the best performance? In this paper, we provide some insights into how to choose an object tracking method from the widespread OpenCV library. We provide benchmarking results on the OTB-100 dataset by evaluating the eight trackers from the OpenCV library. We use two evaluation methods to evaluate the robustness of each algorithm: OPE and SRE combined with Precision and Success Plot.

Die Standsicherheit historischer Mauerwerksbauten muss nicht nur bei gewöhnlichen Einwirkungen, sondern auch während Naturkatastrophen gewährleistet sein. Die seismische Bestandsbewertung der gründerzeitlichen Bausubstanz in Wien ist ein zentrales Thema in der qualitativen sowie konstruktiven Tragwerksbeurteilung. Obwohl der Mauerwerksbau seit vielen Jahrhunderten Anwendung findet, stellt die realistische Tragwerksbewertung eine hochkomplexe Herausforderung dar. Die nach aktuellen Regelwerken zur Nachbemessung herangezogenen Berechnungsmethoden vermögen nur unzureichend das reale Tragverhalten sowie die mögliche Aktivierung der globalen Versagensmechanismen wiederzugeben. Dies führt dazu, dass vereinfachte Nachweise rechnerisch oftmals nur schwer gelingen und zur Kompensation fragwürdige Verstärkungsmaßnahmen ergriffen werden, obwohl der Altbestand bereits einige Beben erlebt und überwiegend schadfrei überstanden hat. Der vorliegende Beitrag befasst sich mit den aktuell zur Erdbebennachbemessung verwendeten Ansätzen und verfolgt den Zweck, Problempunkte aufzuzeigen und sie einem leistungsfähigen, an Versuchsreihen gestützten Materialmodell zur räumlichen Tragwerksanalyse des historischen Altbestandes gegenüberzustellen. Es wird gezeigt, dass die herkömmlichen Berechnungsmethoden für den gemauerten Altbestand ohne Berücksichtigung der Interaktions‐ und Lastumlagerungseffekte sowie der charakteristischen Konstruktionsweise das reale Tragverhalten nur teilweise abbilden. Die Arbeit soll einen Beitrag zur technischen Fachdiskussion zur Erdbebensicherheit des Altbestandes darstellen sowie die Diskussion zur Formulierung realistischer Berechnungsmodelle beleben.

Rails are a part of track structure where corrosion process inevitably occurs, except if they are fully insulated and devoid of contact with any other part of the structure (sleepers, fastening accessories) or electrolyte like moist soil or water in track structure. Corrosion occurs much faster in the presence of stray currents, which very soon results in the loss of material at the rail foot. The paper presents an overview and description of parameters influencing stray current levels, such as electrical potential in rail and longitudinal rail conductivity, rail-to-earth electrical resistance, electrical conductivity of load-bearing concrete layers of truck structure, and electrical conductivity of soil.

Aim To present characteristics of collecting autologous peripheral blood stem cells over a one-year period with an emphasis on efficiency and safety. Methods A retrograde analysis of 24 leukapheresis in 20 adult patients with malignant haematological diseases in the Blood Transfusion Institute of the Federation of Bosnia and Herzegovina in Sarajevo, was done. Cell separators Amicus and Spectra Optia were used for collection procedures. Results The patient's age ranged from 27 to 65 years. Target cells were collected in one procedure in sixteen patients, while in four patients they were collected in two procedures. The mean CD34+ collection efficiency was 57.7%. The median number of CD34+ cells and percentage of CD34+ cells in the products were 5.52x10e6/kg (range 3.28-9.00) and 1.57% (range 0.96-2.91). A strong positive correlation was found between the number of CD34+ cells in peripheral blood on the apheresis day and the amount of CD34+ cells collected in the products (rs =0.73). A total of 95% of patients collected the amount of ≥3x10e6/kg and 55% of ≥5x10e6/kg CD34+ cells for a single transplant. A decrease in platelet count, haemoglobin and haematocrit values after the procedure was not significant. Potassium decrease showed statistical significance (p<0.000). Adverse events occurred during one procedure (4.2%). Conclusion A low number of adverse events and good collection efficiency with adequate patient monitoring, indicate that leukapheresis is a safe procedure that is successfully used in the autologous transplantation process in the treatment of malignant haematological diseases.

Aim Phlebotominae sandflies are primary vectors of phleboviruses, causing the sandfly fever disease. The aim of this study was to detect and report the presence of flaviviruses in Phlebotominae sandflies captured in Bosnia and Herzegovina. Methods After a microscopic and morphometric analysis, the final identification of collected Phlebotomus specimens was confirmed by PCR, using a hemi-nested polymerase chain reaction on extracted and reversely transcribed RNA. Results We obtained a 155 nt long fragment of the viral non-structural protein 5 (NS5) gene (GenBank accession no. MN090154). The acquired nucleotide sequence, provisionally named as Drežnica, showed a maximum of 70-80% identity in 70-88% (110-137 nucleotides) of the query coverage with several Anopheles, Sabethes, Calbertado and Culex flaviviruses. Maximum likelihood phylogenetic analysis showed that the new flavivirus Drežnica clusters together with the flavivirus isolated from Culiseta annulata mosquitos. Conclusion We report the presence of flavivirus in Phlebotominae sandflies, captured in Drežnica, Herzegovina for the first time. The next phase of research will be directed towards virus cultivation, obtaining a longer or complete virus sequence and clarifying the medical and epidemiological importance of the Drežnica virus.

Aim To determine the degree of accuracy in determining the sex of the skull based on classical morphometric analysis of the mastoid process. Morphometric analysis excluded a subjective approach expressed in osteoscopic analysis. Methods The study was conducted on a sample of 100 macerated skulls of known gender and age from the second half of the 20th century, including the Bosnian population. Of the 100 skulls, 50 (50%) were male and 50 (50%) were female. Male skulls were on average 60 (47-71) years old and female 57 (43-76) years old. At each mastoid process, 3 measurements were made: mastoid length, mastoid width (medio-lateral diameter) ML) and anteroposterior diameter (AP) of the mastoid process. Results Using the univariate method, we found a significant difference between length, width, AP diameter and size of mastoid processes as well as between gender (p <0.05). Multivariate binary logistic regression showed statistically significant differences in AP diameter of the mastoid process (p<0.05). Conclusion The created model "P" ("P"=exp [X]/1+exp [X]) for sex determination based on mastoid process showed sensitivity of 82% correct prediction for female skulls and 65% accurate prediction for male skulls. This discourse with respect of population standards grants most effective anthropological proof and as such may be suggested for forensic expertise based on human skull.

Aim Steady progress in intensive treatment worldwide has increased the survival of immature neonates, but with multiple invasive procedures, which have increased the risk of infection, thus the bacterial resistance to antibiotics. The aim of this study was to analyse the epidemiology of multidrug resistance pathogens as causative agents of neonatal sepsis in the neonatal intensive care unit. Methods A retrospective cohort study conducted at the Intensive care unit of the Paediatric Clinic of Tuzla over a three-year period (2016-2018) analysed epidemiology of neonatal sepsis caused by multidrug resistance pathogens. Statistical analysis applied standard methods, and the research was approved by the Ethics Committee of the institution. Results Of the total of 921 treated neonates, multidrug resistance (MDR) pathogens among causative agents of neonatal sepsis were found in 22 neonates (2.38%) with no gender difference. Prematurity and low birth weight were confirmed as the most significant risk factors. From the maternal risk factors a significant difference was found in the first birth and in vitro fertilization. Clinically, MDR sepsis manifested frequently as late onset sepsis, with longer hospital stay and higher mortality. The findings of leukopenia, thrombocytopenia and coagulation disorders were significant. Gram negative bacteria were frequently isolated, in particular Acinetobacter, which showed the greatest resistance to antibiotics. Conclusion Neonatal MDR sepsis is a threat to life, it complicates the treatment, increases costs and mortality. Outcomes can be improved by preventive strategies, earlier and more accurate diagnosis and rational use of antibiotics.

Introduction: Monitoring and diagnosing glaucoma until 2017 included funduscopy, IOP measurements, gonioscopy, pachymetry, as well as visual field tests, optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A). Radial peripapillary capillaries (RPC) can be observed by fluorescein angiography, as well as histologically - superficial and deep capillary layer. Aim: To correlate density of radial peripapillary capillary network (RPC) and retinal nerve fiber layer (RNFL) thickness in eight peripapillary segments in patients with a primary open angle glaucoma (POAG) which have the disease under 10 years of duration, over 10 years of duration and in a group of healthy patients. Methods: This is a cross-sectional review which included three groups of patients: POAG patients under 10 years of disease duration, over 10 years of disease duration and control group of patients. The study is performed on the commercial optical coherence tomography angiography system (AngioVue, Avanti RTVue-XR, Optovue, CA). Sectoral RPC density values, RPC maps and RNFL thickness were analyzed in three groups of patients, data was compared and correlation between parameters was examined. Results: Mean RPC Density values in both superior segments (S1, S2) were significantly lower in patients with glaucoma over 10 years of disease duration compared to patients with glaucoma under 10 years of disease duration (p<0.05). Statistically significant positive correlation was established between RNFL thickness and RPC density in all eight peripapillary segments. Conclusion: Analysis of radial peripapillary capillary network density on optical coherence tomography angiography may provide an earliest functional sign of progressive optic nerve disease and new insights into the pathophysiology of glaucomatous damage.

Abstract In this study, high hydrostatic pressure extraction (HHPE) and ultrasound-assisted extraction (UAE) were used for the improvement of pectin and polyphenol recovery from tomato peel waste. HHPE enhanced pectin recovery by 15% after 45 min of recycling, in comparison with the conventional extraction (CE) for 180 min. Similar mass fractions of anhydrouronic acid, total sugars and total phenols were obtained by using both methods. FTIR and 1H NMR data confirmed that chemical composition of pectin obtained by HHPE and CE is identical, therefore it was concluded that the faster HHPE method can be used for its further isolation. Although depectinized residues subjected to UAE in 70% ethanol for 15 min contained two times lower values of total phenols (1625.7 mg/100 g) than pectinized samples (3643.9 mg/100 g), their quantities are not negligible, considering the fact that they are generated after HHPE. At the end of UAE, the residues were exploited as a source of fatty acids, among which lauric, palmitic and stearic acids are dominant. In conclusion, by shortening the extraction time using HHPE and UAE, it is possible to efficiently produce two valuable functional ingredients, pectin and polyphenols, and at the same time to reduce peel waste from tomato canning industry, which presents an environmental problem. Industrial relevance Utilizing HHPE and UAE as novel and emerging technologies, and combining them with traditional ones (Soxhlet) is given the solution for sequential isolation of pectin, polyphenols and fatty acids from tomato peel waste, generated by canning factory. Shortening of extraction time using HHPE and UAE, it is possible to replace the conventional techniques, and achieve efficient production of pectin and polyphenols. Overall, the extraction methodology proposed in this work could provide two valuable benefits, i.e. the producers could find mode for decreasing of disposal costs of waste and consumer would take opportunity that isolated compounds could be reintroduced into food.

– Eurasian jays ( Garrulus glandarius ) do not habitually use tools, yet they can be trained to solve object-dropping tasks, i.e., to insert a tool into an apparatus to release a food reward. Previous research suggests that these jays can learn a preference toward functional tools – objects allowing them to obtain a food reward placed inside an apparatus – according to their density (Cheke et al., 2011). However, it is not yet known whether they can also select functional tools (tool selectivity) according to other physical properties such as size and shape and use different kinds of tools to solve a similar task. Here we conducted three object-dropping experiments aimed at exploring these abilities in Eurasian jays. In Experiment 1, jays tended to select large stones as tools irrespective of the diameter of the apparatus. However, jays progressively developed a preference for the small tool, which was functional with both the wide and the narrow apparatuses. In Experiment 2, only vertically oriented long stones could fit into the narrow apparatus, whereas both long and round stones were functional with the wide apparatus. Jays showed a preference for the long stone and, with the narrow apparatus, tended to achieve the correct manipulation after one or more unsuccessful attempts. In Experiment 3, jays were able to use sticks and adopt a novel technique on the same object-dropping apparatus, thus providing the first evidence that Eurasian jays can use sticks as tools. Taken together, these results do not support the notion that tool selectivity abilities can be found in Eurasian jays but nonetheless show that these corvids can use different kinds of tools to solve similar tasks.

Background: Oral premalignant lesions (OPLs) represent the most common oral precancerous conditions. One of the major challenges in this field is the identification of OPLs at higher risk for oral squamous cell cancer (OSCC) development, by discovering molecular pathways deregulated in the early steps of malignant transformation. Analysis of deregulated levels of single genes and pathways has been successfully applied to head and neck squamous cell cancers (HNSCC) and OSCC with prognostic/predictive implications. Exploiting the availability of gene expression profile and clinical follow-up information of a well-characterized cohort of OPL patients, we aim to dissect tissue OPL gene expression to identify molecular clusters/signatures associated with oral cancer free survival (OCFS). Materials and methods: The gene expression data of 86 OPL patients were challenged with: an HNSCC specific 6 molecular subtypes model (Immune related: HPV related, Defense Response and Immunoreactive; Mesenchymal, Hypoxia and Classical); one OSCC-specific signature (13 genes); two metabolism-related signatures (3 genes and signatures raised from 6 metabolic pathways associated with prognosis in HNSCC and OSCC, respectively); a hypoxia gene signature. The molecular stratification and high versus low expression of the signatures were correlated with OCFS by Kaplan–Meier analyses. The association of gene expression profiles among the tested biological models and clinical covariates was tested through variance partition analysis. Results: Patients with Mesenchymal, Hypoxia and Classical clusters showed an higher risk of malignant transformation in comparison with immune-related ones (log-rank test, p = 0.0052) and they expressed four enriched hallmarks: “TGF beta signaling” “angiogenesis”, “unfolded protein response”, “apical junction”. Overall, 54 cases entered in the immune related clusters, while the remaining 32 cases belonged to the other clusters. No other signatures showed association with OCFS. Our variance partition analysis proved that clinical and molecular features are able to explain only 21% of gene expression data variability, while the remaining 79% refers to residuals independent of known parameters. Conclusions: Applying the existing signatures derived from HNSCC to OPL, we identified only a protective effect for immune-related signatures. Other gene expression profiles derived from overt cancers were not able to identify the risk of malignant transformation, possibly because they are linked to later stages of cancer progression. The availability of a new well-characterized set of OPL patients and further research is needed to improve the identification of adequate prognosticators in OPLs.

The paper presents an approach aimed at automatically deriving the conceptual database model from a set of business process models. The approach proposes the incremental synthesis of the target model by iteratively composing the partial conceptual database models that are derived from the models contained in the source set. The approach is implemented by the AMADEOS tool, which is the first online web-based tool enabling the automatic derivation of the conceptual database model from a set of business process models.

The combination of 5G and Multi-access Edge Computing (MEC) technologies can bring significant benefits to vehicular networks, providing means for achieving enhanced Quality of Service (QoS), and Quality of Experience (QoE) of wide variety of vehicular applications. Although beneficial in terms of latency reduction, the edge of the architecture for communication networks produces enormous heterogeneity of network services and resources. This challenge becomes even more severe when different administration domains are taken into consideration. Thus, efficient network Management and Orchestration (MANO) of network resources and services are inevitable. As ETSI provided guidelines and standardization for NFV MANO components, the MEC platform can be used to host network services, while MANO systems are in charge of network service management and orchestration. In this paper, we focus on the specific impact that the Virtualized Infrastructure Manager (VIM) has on the performance of the whole MANO system, used for management and orchestration of MEC services and resources in vehicular networks by enabling the on-demand service instantiation, and service teardown. In our testbed-based evaluation, we measured the network service instantiation and termination delays when evaluating: a) OpenStack and Amazon Web Services (AWS) as VIMs for Open Source MANO (OSM), and b) OpenStack and Docker in case of Open Baton. Such performance analysis with a strong experimental component can serve as a baseline for researchers and industry towards exploiting the opportunities that existing MANO solutions provide.