Purpose – Purpose of this study is to understand how diaspora tourists as a specific tourist segment symbolically extend their holiday in the country of origin upon returning to the country of current living. Methodology – Aim of the research was to disclose underlying meanings of this specific consumption pattern. Data was collected through 24 semi-structured in-depth interviews with diaspora members from Bosnia and Herzegovina. Analysis was inductive, starting with microanalysis, proceeding then with axial coding around the revealed concept. Throughout analysis the comparative method was applied, alongside researcher's diary and memos as analytic tools. Findings – The concept of ‘bridging’ explains how diaspora tourists cross over from one reality to another on a symbolical level, i.e. when travelling back from the country of origin. It also is a symbolical bridging between complex of identities: the past identities and the present identity, which they have constructed in countries of current living. They seem to use two major strategies: storytelling and product stocking. Contribution – This paper reveals a new concept among diaspora tourists, i.e. their approach to extend their visit to the country of their origin on a symbolical level by using symbolically laden products. The research is further contributing by disclosing that diaspora tourists apply two different strategies in order to symbolically extend their home country holiday: the story telling strategy and the stocking strategy. Finally, it also suggests that the stocking strategy has two phases; the first phase being 'symbolic representation filling phase' and the second phase labelled as 'mainstream trend purchase phase'.

Background: Breast cancer in women is the second most common and accounts for approximately 18% of all malignant tumors in women worldwide. The etiology of breast cancer is not clear enough. Starting from the assumption that the manifestation of breast cancer may have a multifactorial model, this article compares the population-genetic structure of patients (experimental group) with the population-genetic structure of healthy population (control group). Objective: The aim of the study was to examine the possible genetic basis of the Rh factor relationship with selected homozygous-recessive traits of females with breast cancer, and to diagnose the probability (assess the risk) of developing the disease in healthy women by analyzing homozygous-recessive traits (HRT). Methods: This are an anthroposcopic-qualitative study that included two groups of subjects, experimental and control (a total of 80 subjects). An analysis of the percentages within each group was performed using the Chi-square test. The results are presented in tables, and the accepted level of significance is at the level of p <0.05. Results: In the group of Rh+ subjects, the correlation of this type of Rh factor with the breast cancer was proven, given the frequency of the phenotype of homozygous-recessive traits in them. A statistically significant difference was found for 4 traits, and three are also close to the set significance level. In subjects with Rh- factor, a statistically significant difference was found for only one trait (absence of mallets on the phalanges). Conclusion: Although the number of subjects was relatively small, we can conclude that in the experimental group a higher frequency of recessive phenotypes for the examined traits was recorded, which indicates the genetic load of the subjects from this group. Correlation with Rh factor was observed in the case of subjects of the experimental group with Rh+ factor.

Abstract The adrenal abscess is a rare complication of adrenal hemorrhage in the neonatal period. Due to its rare occurrence and non-specific signs, diagnosing and treating an adrenal abscess in the neonatal period might be challenging. We present herein a 3-week-old male neonate with an adrenal abscess associated with Escherichia coli sepsis, which was successfully treated by open surgery (using the minimal posterior lumbar approach) following an unsuccessful ultrasound-guided percutaneous drainage.

Purpose – The purpose of this paper is to examine the effects that COVID-19 outbreak has had on tourism in Bosnia and Herzegovina (BiH) and specifically in Sarajevo Canton. Methodology – A survey was conducted in two rounds in March and September 2020, and responses were obtained from 126 running businesses from the tourism in Sarajevo Canton about the actual and expected consequences that COVID-19 outbreak has had on their business. The respondents were asked questions about the effects that COVID-19 has had on their business operations during the first six months of COVID-19 outbreak and their expectations for the future. The questions also included issues related to the government interventions and stimulus packages to overcome the effects of COVID-19 to ensure the sustainability of the tourism in Sarajevo Canton. Findings – Our results show that all businesses have faced a significant downturn in their business operations and had to undertake different measures and activities internally to overcome (and survive) the negative effects of the COVID-19 pandemic. The results also show that there is very low level of satisfaction with the government interventions to tourism. Contribution – The findings illustrate and confirm many flaws in tourism system in Sarajevo Canton and BiH where tourism has been developing organically and without proper integration of the private and public industry. Our findings can be used for planning purposes and improvement of the situation during COVID-19 and post-COVID-19 period.

. We present data on NAb and T cell responses against whole live virus, including wild-type SARS-CoV-2 (WT), Beta, and Delta VOCs. We

Abstract Large corporate scandals in the US and Europe, from the early 21st century, such as Enron, Parmalat, WorldCom and many others, have seriously shaken public confidence in the auditors’ work. Consequently, many countries have recognized the need for introduce the forensic accounting as a more advanced and reliable form of protection against manipulative financial reporting by companies, and have completed the accounting profession with the forensic accountant title, as an active fighter against various types of frauds in companies.

Genetic variants in FOXO3 are associated with longevity. Here, we assessed whether blood DNA methylation at FOXO3 was associated with cancer risk, survival, and mortality. We used data from eight prospective case–control studies of breast (n = 409 cases), colorectal (n = 835), gastric (n = 170), kidney (n = 143), lung (n = 332), prostate (n = 869), and urothelial (n = 428) cancer and B-cell lymphoma (n = 438). Case–control pairs were matched on age, sex, country of birth, and smoking (lung cancer study). Conditional logistic regression was used to assess associations between cancer risk and methylation at 45 CpGs of FOXO3 included on the HumanMethylation450 assay. Mixed-effects Cox models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations with cancer survival (total n = 2286 deaths). Additionally, using data from 1088 older participants, we assessed associations of FOXO3 methylation with overall and cause-specific mortality (n = 354 deaths). Methylation at a CpG in the first exon region of FOXO3 (6:108882981) was associated with gastric cancer survival (HR = 2.39, 95% CI: 1.60–3.56, p = 1.9 × 10−5). Methylation at three CpGs in TSS1500 and gene body was associated with lung cancer survival (p < 6.1 × 10−5). We found no evidence of associations of FOXO3 methylation with cancer risk and mortality. Our findings may contribute to understanding the implication of FOXO3 in longevity.

An increasing number of studies have revealed that dysregulated lipid homeostasis is associated with the pathological processes that lead to Alzheimer’s disease (AD). If changes in key lipid species could be detected in the periphery, it would advance our understanding of the disease and facilitate biomarker discovery. Global lipidomic profiling of sera/blood however has proved challenging with limited disease or tissue specificity. Small extracellular vesicles (EV) in the central nervous system, can pass the blood‐brain barrier and enter the periphery, carrying a subset of lipids that could reflect lipid homeostasis in brain. This makes EVs uniquely suited for peripheral biomarker exploration.

Introduction: Nosocomial infections are a global problem in the health care system, but they more affect lowand middleincome countries. Educating healthcare professionals about nosocomial infections and prevention strategies to have a significant impact on reducing the number of infections. Aim: To determine and compare students' knowledge and attitudes about nosocomial infections and prevention strategies at the Faculty of Nursing and Sanitary Engineering from the Faculty of Health Studies and the School of Medicine. Method: This is a cross-sectional study. The sample consisted of 150 students of third and fourth academic years, both sexes, from the Department of Nursing (n = 50), Department of Sanitary Engineering (n = 50) of Faculty of Health Studies and the School of Medicine (n = 50). The survey was conducted using a self-designed survey questionnaire, divided into three sections: knowledge of nosocomial infections, knowledge of hand hygiene, beliefs, and attitudes about the effect of education on nosocomial infections. Each unit had 5 statements, and the possibility of answering with "YES" or "NO". Result: Students of all three studies showed, on average, good knowledge of the occurrence and prevention of nosocomial infections. The post-hoc comparison showed significantly higher knowledge of students from the School of Medicine and Sanitary Engineering compared to the knowledge of students from the Department of Nursing (p <0.005), but not in the hand hygiene test. In the hand hygiene test, a significant difference in overall knowledge was found between the School of Medicine and Sanitary Engineering, in favor of the School of Medicine (p = 0.037). Most students from all faculties are convinced that knowledge of nosocomial infections and adherence to prevention measures is an important strategy in their prevention. Conclusion: The knowledge of the health-oriented faculties of the University of Mostar is satisfactory. Nevertheless, many students at all faculties consider that education at faculties is insufficient.

Food costs are the highest costs in milk production so they need to be minimized. In large dairy farms, the total share of food in the cost structure ranges from 50-60%, while in small farms it is above 60%. By producing one's own voluminous food, the sustainable needs of animals and lower milk production can be met, while higher milk production requires the use of concentrated nutrients produced on one's own farm (corn, cereals). The purchase of ready-mixed feeds should be avoided because it is economically unjustified. Poorer quality and inadequate quantities (more or less than technological needs) in the diet of dairy cows have a direct effect on the amount of milk produced, and thus on income. The production of own fodder and its use greatly reduces the cost of milk because the internal factors of the farm's business determine the success of the business more than the selling price. The cost of food in the total cost of milk production participates from 44.50% in small farms that have a grazing system in the feeding, to 56.71% in Holstein cows in 2021. The share of concentrate in the total cost of feeding is from 55.80% in Holstein cows in 2020 to 71.23% in small farms with a grazing system in the feeding. The costs of production of corn silage in the feeding ratio in 2020. yaer amounted 0.0514 BAM / kg, and in the feeding ratio in 2021. Year 0.0433 BAM / kg. The price of concentrate in the feeding ratio in 2020. Year was 0.55 BAM / kg, and in 2021. Year 0.72 BAM / kg (1 BAM = 0,511 €) (1 BAM = 0, 59 $) The coefficient of economy is from 1.4920 in farms with up to 10 Simmental cows, to 1.8214 in larger Holstein cow farms.

By seed surfaces according to the information the Federal Bureau of Statistics and the Institute of Statistics Republic of Srpska of the total area under vegetables potatoes occupies 57% sowing area, so that after the corn and wheat, potatoes the most important agricultural plant in Bosnia and Herzegovina. Most are lighter types of land - permeable, loose, sandy-humus and sandy-clay ground with crumb structure, rich in mineral and organic matter, with favorable water – air characteristics. Does not match his tough swampy lands with a high level of underground water. Tolerate acid soil reaction, and the optimum pH is 5,4-6,5. Given that the area of Tuzla canton mainly acid soil with pH values from 4.5 to 5.5 made the production of a sample on the plot that had a pH value of 4.6 as a material for the reparation of land or quality of calcification was Fertdolomit in order to increase in pH, after you apply Fertdolomit analysis has found that the increased pH value to 5.8. Calcification is a measure of repair of chemical properties of soil, primarily reducing its acidity, ie. bringing the pH value to the optimum level for the cultivation of certain plant species calcium use of fertilizers. At the same time, this measure of the repair water-air, mechanical, physical and biological properties of soil. Reflected in the potatoes plant in four different variants: the control, with the use of 40 t / ha of manure, the use of 40 t / ha manure and NPK 7:20:30 400 kg / ha and the use of manure 40 t / ha, NPK 7:20: 30 in the amount of 400 kg / ha with supplements Fertdolomit in the amount of 3 t / ha. The results reflected a big point to the importance of calcification in the production of potatoes.

BACKGROUND In the first year of studies, students face many changes. On one side is the demanding medical education, and on the other side, is to find a balance with old friends, parents, and a new social environment. These changes may result in psychological symptoms such as anxiety or depression, which is the most commonly, reported mental disorder among students. This study intended to explore the presence of anxiety and depression symptoms in first-year medical students and investigate how family cohesion, flexibility and psychosocial factors influence anxiety and depression. METHODS 149 medical students (76.5 % females and 23.5 % males) took part in a crosssectional study. The survey was conducted via the sociodemographic questionnaire, Multidimensional Scale of Perceived Social Support, Rosenberg Self-esteem Scale, the short version of Loneliness Scale, Family Adaptability & Cohesion Scale, Beck Anxiety Inventory, and Beck Depression Inventory. RESULTS The prevalence of moderate and severe anxiety and depression symptoms among medical students was 53.8 % and 19.5 %, respectively. Female students experienced higher levels of anxiety and depression compared to their male colleagues. Students who had physical activities at least once a week showed significantly lower anxiety and depression scores. Anxiety and depression were positively associated with loneliness and negatively associated with perceived social support from family and self-esteem. Depression was also negatively associated with family cohesion and adaptability. Moreover, the results revealed that family cohesion was a strong predictor of the severity of depression symptoms. CONCLUSIONS This study shows that variables such as gender, physical activities, feeling of loneliness, low self-esteem, and perceived social support from family play an important role in the experience of anxiety and depression among medical students. This study raises awareness about mental disorders in medical students, especially anxiety and depression, and invites the placement of these problems among the top priorities of public health policies. KEY WORDS Anxiety; Depression, Family Relations, Students

Introduction: The coronavirus disease 2019 (COVID-19) pandemic has put national health systems under extremely large pressure. Health systems throughout the world demonstrated different levels of preparedness for COVID-19 pandemic. Aim: The aim of the study was to investigate the association of resilience with quality of life and self-esteem in healthcare workers of COVID-19 hospital. Methods: We performed a cross-sectional study between November 2020 and February 2021 in COVID-19 hospital at the University Clinical Hospital Mostar. A socio-demographic questionnaire specifically designed for this study, a CD-RISC25 scale for assessing resilience, a WHOQOL-BREF questionnaire for assessing quality of life, and a RSES scale for assessing self-esteem were used for collecting data. Results: A statistically significant higher resilience was in healthcare workers who felt adequately prepared for work in COVID-19 hospital. Resilience, quality of life and self-esteem statistically significantly positively correlated with one another among healthcare workers. A healthcare worker’s resilience level was statistically significantly affected by psychological domain of the quality of life, gender, and adequate preparation. Conclusion: Resilience is positively related to the quality of life and self-esteem in healthcare workers of COVID-19 hospital at the University Clinical Hospital Mostar.