Scabies is very often parasites dermatosis. Diagnostic problems are not rare considering the fact that the clinical picture of scabies in infant population is different compared to the adult population. The scabies that is untreated or non-adequately treated has a long course followed by complications. In hospital in Tuzla in a period 1995-1997 we have done retrospective study which included 64 infants with scabies followed with complications. Skin changes have appeared approximately 2-6 months before admission to the hospital. In 55.3% cases the scabies stayed unrecognized and the aforementioned patients were treated under other diagnosis: Dermatitis allergic 50%, Piodermia 30%, Dermatitis seborrhoica 10%, Dermatosis 10%. Problem is the medical treatment of only sick child, and not of complete family. That makes possibility for inter-family infestation and prolongs course of scabies as disease as well as its medical treatment. In infants with skin changes we should also consider possibility of infection by parasite Sarcoptes scabiei var. hominis. Medical treatment and appropriate diagnostic as well as treatment of all members of the families without the matter of existence of skin changes makes the course of disease shorter.

AIM Immunohistochemical study of carcinoembryonic antigen (CEA) distribution in inflammatory-regenerative and dysplastic changes of bowel mucosa. The relationship between the presentation of CEA and the intensity of inflammatory-regenerative and dysplastic processes in the flat colon mucosa was also examined. METHODS Biopsy specimens from 105 patients were examined: 45 classified as inflammatory-regenerative and 60 as dysplastic (21 mild, 23 moderate, and 16 severe dysplasia). The expression of CEA was assessed on the basis of location, quantity, and intensity of CEA immunostaining, by counting antigen-positive cells, and the presence of antigen in the lumen of crypts and glycocalyx on the surface of the mucosa. Using a semiquantitative method, antigen staining intensity was defined as weak, moderate, and intense. RESULTS The quantity of CEA in columnar, goblet mucous, and undifferentiated cells, as well as in the glycocalyx on the surface of the mucosa and in the crypts' content increased proportionally with the intensity of epithelial dysplasia. In inflammatory-regenerative lesions, CEA was located in the apical and supranuclear part of the cytoplasm, and in the dysplastic mucosa, in lateral and basal parts of the cells. CONCLUSION The quantity of immunohistochemically demonstrable CEA and its intracellular distribution changed in the colon mucosa during the transition from regenerative to dysplastic epithelial lesions. The intensity of CEA expression was closely related to the intensity of dysplastic lesion.

Recently, thanks to the collected knowledge and increased diagnostic abilities we more often meet the diseases that have been considered very seldom. Beside that, we form the new assumptions that must be proved. Today, more often we meet gastric mucosa in duodenum. That according to some researchers, introduces a real possibility for appearance of the polyps, ulcers or cancer on gastric substratum. In the subject patient the two polyps of the gastric origin were found in a duodenum. That could support the assumption that ectopic gastric mucosa presents one of the real possibilities for appearance of polyps, ulcers and cancer.