The densities and viscosities of synephrine hydrochloride and octopamine hydrochloride aqueous solutions were determined. Apparent molar volumes, apparent molar volume at infinite dilution, viscosity B-coefficients and hydration number were calculated, and it was found that synephrine hydrochloride acts as a better structure maker than octopamine hydrochloride in aqueous solutions. The densities of the investigated salts were measured in aqueous d-fructose solutions, and the corresponding apparent molar volumes of transfer at infinite dilution were determined. Its taste behavior was discussed based on the calculated values for apparent specific volume and intrinsic viscosity. Molecular dynamics simulations and radial distribution functions were applied in order to understand the nature of the interactions and water structuring in the studied systems. The change in taste behavior was observed with increasing concentration of the cosolute, and it was found that the addition of sugar increases the bitterness of the solution. From a molecular docking study on the bitter receptor TAS2R38, the strongest interactions for synephrine-HCl were noted causing the most bitter taste.

Introduction: Pneumothorax is a life threatening condition, more often seen in immature infants receiving mechanical ventilation. It carries a significant risk of death and impaired outcome. Objective: To determine predictive factors for the occurrence of pneumothorax in preterm infants with respiratory distress syndrome (RDS). Patients and methods: The present study was conducted in a tertiary research and educational hospital, NICU, Pediatric Clinic UKC Sarajevo, from January 2010 to December 2013. All infants had chest X-ray at admission, and were treated due to RDS with nasal continuous positive airway pressure (CPAP), mechanical ventilation, or high frequency oscillatory ventilation. At admission we registered data regarding birth weight, gestational age, Apgar score, prenatally given steroids. Inclusion criteria were fulfilled by 417 infants. Data about timing, circumstances, side and treatment of pneumothorax were gathered from medical records. Results: Mean birth weight was 1,477 g, mean gestational age 29.6 weeks. We report 98 infants who did not survive. We also report incidence of pneumothorax in 5% of the infants with RDS. In this study pneumothorax and non-pneumothorax groups didn’t differ regarding sex, gestational age (median 29 and 30) nor birth weight (p = 0.818). Apgar score at the 1 st and 5 th minute of life had no influence in genesis of pulmonary air leak, neither prenatally given steroids (p = 0.639), nor surfactant administration. There was a low coverage of preterm infants with prenatal steroids (overall 28.29%). We found that FiO 2 ≥ 0.4 in the first 12 hours of life, and need for mechanical ventilation are predicting factors for developing pneumothorax (p < 0.05). Conclusion: Together with mechanical ventilation, inspired fraction of oxygen higher than 40%, needed to provide adequate oxygenation in the first 12 hours of life in preterm infants, could be a predictive factor in selecting the highest risk babies for development of neonatal pneumothorax.

Haemodialysis is a fast and efficient meth-od for removing toxins from the body in a straightforward manner. This has been a regular practice at the Paediatric Clinic in Sarajevo, Department of Paediatric In-tensive Therapy since January 2009. By December 2014 there were 34 patients treated by haemodialysis, who had un-dergone 253 haemodialyses in total. There were 18 (52.9%) primary nephrologic pa-tients, while 16 (41.05%) were patients whose renal failure was caused by other etiology. The main objective of this paper is to present the most common conditions in childhood that require haemodialysis in its treatment. The Department of Paediat-ric Intensive Therapy for this period had hospitalized 1,226 patients in total. Out of this number 2.77% of patients required the application of haemodialysis in their treat-ment. The results show that the most common renal causes to perform haemodialysis are: haemolytic uremic syndrome (HUS), chronic renal failure, nephrotic syndrome and congenital bilateral nephrolithiasis. For the others, the most common non-renal causes are multiple organ dysfunc-tion syndrome (MODS) that occurs as a result of cardiac insufficiency, hepatic in-sufficiency or after surgeries, as well as in hemato-oncologic diseases.

In this research 245 cows are included. They are daughters of ten sires and all of them realized 548 lactations in the period 2000 and 2003. Data used originated from two cattle farms, "Backa" and "Pobeda" that are on government property "Krivaja". During lactation lasting approximately 333 days cow produced 4521 kg of milk yield with 181 kg fat yield and 4,00% fat percentage in standard lactation. The values for heritability are estimated by using interclass correlation. It was low for duration of lactation (0,017) and for fat percentage (0,037). Also, it was medium for milk yield (0,227) and fat yield (0,214).The average values for heritability in the standard lactations were 0,317 for milk yield and 0,281 for fat yield. In other words, those are medium hereditary features. The values for heritability were low for fat percentage (0,031), or low hereditary feature.

In this research 245 cows were included. They are daughters of ten sires, and they realized 548 lactations in the period from year 2000 to 2003. Data were used from two cattle farms, "Backa" and "Pobeda" that are located on government property "Krivaja". In this research influences of systematic factors like farm, year, season or lactation have been included. Breading values are evaluated for all qualities (milk yield, fat yield, fat percentage and persistency of milk production). Sires are ranked based on average milk yield of his daughters.

In this research 245 cows are included. They are daughters of ten sires, and all of them realized 548 lactations in the period 2000 and 2003. Data were used from two cattle farms, "Backa" and "Pobeda" that are on government property "Krivaja". At first hundred days, cows produced approximately 1770 kg milk yield, and during the period of first two hundred days, cows produced about 3173 kg milk yield. The milk yield in monthly controls which were made approximately at 29,4 days, was 399 kg, which means 11,73 kg per day. Persistency of milk production was done by index R2:1 and the average amount of milk was 79,57%.