SUMMARY Objective: Aim of this project is to establish blood glucose level of workers who are by occupationally exposed to noise, to establish correlations between degree of damage of sense of hearing and blood glucose level of exposed workers and correlations between duration of exposure and levels of disturbances of glucose. Patients: Examination included 235 workers. After applying strict criteria for inclusion or exclusion, 81 workers (male and female) have been selected. In control group there were 50 clerks (male and female) who were not exposed to industrial noise. Methods: Audiometric examination was performed using apparatus AMPLAID 171. Examination of level of glucose was performed using apparatus DIMENSION POND PLUS by method glucoso-6-phosphat dehydrogenase (hexokinase). Body height and mass was determined by anthropometric measurement and BMI was calculated using standard formula. Results: This examination analyses effect of industrial noise on hearing and effects on level of blood glucose. The results were determined by correlation method and show that workers exposed to industrial noise for years, have higher damage of hearing sense and higher level of blood glucose than those workers who were not exposed to the noise.

The coronary illness is the first cause of death and falling ill in the world. It is considered that, in more than 50% of cases, it is about the illnesses of heart and blood vessels as the cause of death. These results indicate the necessity to prevent and to treat correctly the persons suffering from cardivascular illnesses. The coronary illness represents the ischaemia myocardium as the consequence of reduced blood flow through the coronary arteries (one or more branches). There are more and more young persons suffering from this illness. In the Emergency Medical Institute Sarajevo, a retrospective-prospective analysis of patients with working diagnosis of ACS was carried out for the period of one year (01.01-31.12. 2008). The patients (279) were analyzed by gender, years of age, months (*when ACS occurred), seasons of year and hours of occurrence of ACS, therapy by applying low-molecular heparin and prospectively by symptoms, as well as usual risk factors.

GOAL OF THE STUDY To determine the changes of the electroencephalogram and the changes of the quantity in percentage terms of alpha, beta, theta and delta waves in the electroencephalogram in migraine patients after a carbamazepine treatment. Analyze pain characteristics after the carbamazepine treatment of these patients and the efficiency of the carbamazepine treatment in the prevention of new attacks. PATIENTS, METHODS, RESULTS A retrospective-prospective study has been conducted on 40 persons of approximately 42,9 years of age, with normal cranium CT finding, craniogram and fundus. They were divided in two groups: Group A--21 person who prophylactically took a daily dosage of 400 mg Carbamezepin and during acute pain attacks Naproksen; and group B--19 persons who prophylactically took daily dosage of 400 mg Carbamezepin. EEG test was done twice--before and after the medication, in order to check the concentration of different waves in the EEG in percentages. The T-test doesn't show a statistically significant difference between the alpha (p 0,719), beta 1 (p 0,865), beta 2 (p 0,710), theta (p 0,867) and delta (p 0,272) waves for the group A and for the group B alpha (p 0,996), beta 1 (p 0,920), beta 2 (p 0,826), theta (p 0,324) and delta (p 0,820) waves, on the significance level p 0,05 in the EEG at the beginning and the EEG at the end of the examination. The t-test does show a statistically significant difference between the intensity, frequency, duration and relief of pain at the beginning and at the end of the examination for both test groups. CONCLUSION Carbamazepin and Paracetamol do not cause changes in the EEG nor in the quantity in percentage terms of concentration of different waves in the control EEG in patients with vascular headaches. Statistically Carbamazepin and Paracetamol significantly change characteristics of pain and can be used for migraine treatment and prophylaxis.

UNLABELLED Headache can be manifested as primary disorder or it is a secondary symptom of some other illnes. Electroencephalography (EEG) is electrodiagnostic method which registers electric activity of brain cells and by this method therapeutic effect of single medicaments can be followed by comparing of EEG before and after medication. The aim of work was to test if there are changes in EEG in headaches under the influence of naproxen and sumatriptan in the acute attack of headache and during the prevention of often attacks of pain. PATIENTS, METHODS AND RESULTS The retrospectiveprospective study was conducted on 92 patients, average age of 42.9 with regular CT of cranium, craniogram and fundus. They were divided in two groups based on drugs they were taking for the prevention or treatment of acute attack of pain. Group A 44 patients preventively took naproxen in the daily dose of 550 mg and in acute attack of pain sumatriptan and group B 48 patients in the acute attack of pain took sumatripanin one dose of 50 mg. Two EEG were recorded before and after medication and concentration of certain waves in EEG was followed. Statistics proved that there is no statistic difference in the EEG before and after medication. Hi square test (Hi Sq. = 1.087) does not show statistically important difference within the number of patients divided in groups, significance is on leve p = 0.297. T-test does not show existence of statistically important difference between concentration of Alpha, beta, teta and delta waves in starting EEG and in EEG at the end of testing after taking on Naproxen 550 mg daily for one month for group A and a pill of Sumatriptan in the acute attack for group B. CONCLUSION It means that naproxen and sumatriptan at patients with headaches do not cause changes in EEG, nor percent concentration of single waves in starting and control EEG and statistically significant reduce pain at tested patients with vascular headaches.

Migraine is periodical disorder which is characterized by recurrent headache seizures different in intensity, frequency and duration. Amylases L-1,4 glycol: gluckanohidrolises, (EC.3.2.1.1) are enzymes from hydrolase's group which dissolve starch meaning glycogen. Activity of amylases in serum grows: at acute pancreatitis, at carcinoma of pancreas, heavy necroses of pancreas. Total number of examinees was 92 out of which 45 were male (48.9 %) and 47 female or 51.1 %. Average age of the examines was 42.9. Neuroticism scale which was tested by Cornell scale was 55,03. Out of the total number of examinees 30 or 32,6 were non-smokers while 62 or 67,4 % smoked regularly. The aim of this work is to perform hematological-biochemical test of blood in patients with migraine. In the beginning of this research it was planned for all the patients to have hematological blood test done (sedimentation of erythrocytes, trombocytes, complete blood test and differential blood test) and biochemical blood test (hepatogram, transamynase, amylase, Lactal dehydrogenase, Alkalic phosphatase, ferrum in serum, Glucose, Cholesterol, Calcium and Phosphorus in serum. After reviewing the received values of hematological and biochemical tests, all values were within the borders of normal values. Amylases had higher values at 49 or 53,3 % of patients, and 43 or 46,7 % of patients had normal values of amylases. Normal values of amylases are to 220 U/l measured by I.F.C. at 37 degrees C. Medium value in tested group is 219.09. It means that every second examinee had increased values of amylase in blood; there is no statistics difference of amylase value between sexes.

: Migraine is periodical disorder which is characterized by recurrent headache seizures different in intensity, frequency and duration. Amylases L-1,4 glycol: gluckanohidrolises, (EC.3.2.1.1) are enzymes from hydrolase's group which dissolve starch meaning glycogen. Activity of amylases in serum grows: at acute pancreatitis, at carcinoma of pancreas, heavy necroses of pancreas. Total number of examinees was 92 out of which 45 were male (48.9 %) and 47 female or 51.1 %. Average age of the examines was 42.9. Neuroticism scale which was tested by Cornell scale was 55,03. Out of the total number of examinees 30 or 32,6 were non-smokers while 62 or 67,4 % smoked regularly. The aim of this work is to perform hematological-biochemical test of blood in patients with migraine. In the beginning of this research it was planned for all the patients to have hematological blood test done (sedimentation of erythrocytes, trombocytes, complete blood test and differential blood test) and biochemical blood test (hepatogram, transamynase, amylase, Lactal dehydrogenase, Alkalic phosphatase, ferrum in serum, Glucose, Cholesterol, Calcium and Phosphorus in serum. After reviewing the received values of hematological and biochemical tests, all values were within the borders of normal values. Amylases had higher values at 49 or 53,3 % of patients, and 43 or 46,7 % of patients had normal values of amylases. Normal values of amylases are to 220 U/l measured by I.F.C. at 37 degrees C. Medium value in tested group is 219.09. It means that every second examinee had increased values of amylase in blood; there is no statistics difference of amylase value between sexes.

Patient with diabetes is susceptible to development of vascular lesions of the blood vessels of all sizes. During the discase there is a progressive development of microangiopatys and arterioscleroses. Continuing the works of Stanley I., Rapaport and other rescarches about changes of permeability of hcmatoenchepal barrier in experimental conditions, (according1) the changes of the barrier at patients with diabetes mellitus was examined in this work. At the patients with diabetes mellitus level of sodium in liquor increases, and the level of chlorine and potassium in liquor decreases.

Patient with diabetes mellitus is prone to develop the vascular lesion of blood vessels of all kinds. Microangiopathy and atherosclerosis are progressive during the illness. Also with this study blood brain barrier change in the diabetes mellitus patients was observed. In patients with diabetes mellitus the level of glucose and total proteins increased in the cerebrospinal fluid. During diabetes mellitus the change of permeability blood brain barrier is evident. Blood brain barrier permeability changes in the patients with ICV as well as in the patients without ICV correlate with the values of diabetes mellitus in blood.

Patient with diabetes mellitus is prone develop vascular lesion of blood vessels of all kinds. Microangiopathy and atherosclerosis are progressive during the illness. Following the study of Stanley I. Rapport the at all scientist on blood brain barrier permeability change in experimental conditions, also with this study blood brain barrier change in the diabetes mellitus patients was observed. In patients with diabetes mellitus the level total proteins increased in the cerebrospinal fluid.