Today, at the era of information technologies Bosnia and Herzegovina does not have organized action for creation of standardized Computer-Based Information Systems (CBISs) in health. These CBISs would enable collection of defined and comparable data and therefore ensure adequate analysis, observation and decision making on a local community level as well on the general level of health information system. Thanks to enthusiasts, local CBISs are created in health care facilities. Those individual local CBISs have similar solutions based on the experience of previous good functioning. Therefore, we can expect that a standardized state CBIS will be formed with the minimal focused action of people in charge. The Zavidovici Medical Center has a CBIS which has been working long enough so that we can analyze the results of usage of such an information system. The system has a modular character, oriented on analysis and documentation of data, and on support for management and decision-making functions. Analyzing the results reached by implementation of such a CBIS, we can conclude that we have achieved better results in patient administration and work organization and that we have less patients in dispensary of primary health care by 20%, shorter time in treatment of patients by 7%, reduced consumption of essential medicines by 8%, costs of treatment in medical facilities are down by 5% and patients have more a positive view toward the services provided now than they had earlier. Moreover, substantial savings in radio and laboratory diagnostics procedures have been achieved by reducing time for doing lab reports, savings in materials and through minimizing human error.

CONFLICT OF INTEREST: NONE DECLARED New discoveries in technology indeed enabled significant improvement of health care in the last three decades. Only during the last few years a significant breakthrough is achieved in the field of antiviral drugs, biotechnology, digital diagnostic technology, molecular diagnosis, tissues and organs transplantation as well as surgical and information technologies, which all contributed to the improvement of health care. Rapid growth of medical technology has led to the increase in costs of health care, increased access to these technologies and improvement of health care that is permanently encouraging the further development of technology. Technology encompasses the skills, knowledge and ability to understand, use and create useful things. It is the practical application of knowledge. Evaluation of health technology is the systematic evaluation of characteristics, results or impact of health technologies. The primary purpose of evaluation is to provide information to responsible parties for the technology in the health care system, which will be used in decision-making and introduction of these technologies. Information technology in medicine and health care represents all medical and health technology in the process of work, monitoring and evaluation done using computer technology. Progress of medical science in recent years especially needs to thank to the development of information technologies. The health care system of Bosnia and Herzegovina is currently operating in the two sub-systems of primary health care. One is inherited from the past system, in which the primary health care is provided by general practitioners, specialists in general practice, as well as gynecologists, pediatricians and pulmologists, and the second subsystem occurs when in PHC is introduced the system of family medicine doctors and family medicine specialists. Family medicine, based on the concept of orientation towards the methods which are more effective, rational and cost-effective health care, use of defined procedures and evidence-based medicine, and more adequate education can empower and stimulate general practice doctors, especially family medicine specialists, who have passed various forms of training and courses in this area, to more rational and efficient use of diagnostic technology in their daily practice, without unnecessary duplication of tests. With this they make savings to the healthcare system, improve the financial position of overall health system, especially in the PHC segment, increase satisfaction of doctors providing that health care, but also the users of health services.

New discoveries in technology indeed enabled significant improvement of health care in the last three decades. Only during the last few years a significant breakthrough is achieved in the field of antiviral drugs, biotechnology, digital diagnostic technology, molecular diagnosis, tissues and organs transplantation as well as surgical and information technologies, which all contributed to the improvement of health care. Rapid growth of medical technology has led to the increase in costs of health care, increased access to these technologies and improvement of health care that is permanently encouraging the further development of technology. Technology encompasses the skills, knowledge and ability to understand, use and create useful things. It is the practical application of knowledge. Evaluation of health technology is the systematic evaluation of characteristics, results or impact of health technologies. The primary purpose of evaluation is to provide information to responsible parties for the technology in the health care system, which will be used in decision-making and introduction of these technologies. Information technology in medicine and health care represents all medical and health technology in the process of work, monitoring and evaluation done using computer technology. Progress of medical science in recent years especially needs to thank to the development of information technologies. The health care system of Bosnia and Herzegovina is currently operating in the two sub-systems of primary health care. One is inherited from the past system, in which the primary health care is provided by general practitioners, specialists in general practice, as well as gynecologists, pediatricians and pulmologists, and the second subsystem occurs when in PHC is introduced the system of family medicine doctors and family medicine specialists. Family medicine, based on the concept of orientation towards the methods which are more effective, rational and cost-effective health care, use of defined procedures and evidence-based medicine, and more adequate education can empower and stimulate general practice doctors, especially family medicine specialists, who have passed various forms of training and courses in this area, to more rational and efficient use of diagnostic technology in their daily practice, without unnecessary duplication of tests. With this they make savings to the healthcare system, improve the financial position of overall health system, especially in the PHC segment, increase satisfaction of doctors providing that health care, but also the users of health services

Area of Zenica Doboj Canton (ZDC), as well as other areas in Bosnia and Herzegovina, due to geographic, climate and agricultural features, also because of the fact, that animal farms and human habitats are closely related, as well as due to the poor hygiene conditions in places with dominant sheep farming, have fruitful conditions for endemic persistence and spreading of brucellosis, as a typical zoonosis. Lack of systematic research about farms that keeping the animals, and Program of control and suppression of brucellosis, as well as other veterinary measures in order to control the health of domestic animals, in order to protect the health of the human population, have the consequence in continuous presence of brucellosis among animals and humans in this area. As the confirmation of this is also the data about the frequency of this disease in the period 2000-2007, is analyzed in this paper. Follow up and control of brucellosis within human population in ZDC during the period observed showed continuous presence of brucellosis with changing morbidity rate and with the tendency for increasing in this period. During observed time period also noticed was the epidemic occurrence of this disease in two municipalities with the largest number and concentration of herds and sheep farms in ZDC (Zenica and Zepce). In total during the epidemic and non epidemic period we registered 294 patients. The number of occasional cases is contained within the total number of cases reported during epidemics.

GOAL OF THE STUDY To determine the changes of the electroencephalogram and the changes of the quantity in percentage terms of alpha, beta, theta and delta waves in the electroencephalogram in migraine patients after a carbamazepine treatment. Analyze pain characteristics after the carbamazepine treatment of these patients and the efficiency of the carbamazepine treatment in the prevention of new attacks. PATIENTS, METHODS, RESULTS A retrospective-prospective study has been conducted on 40 persons of approximately 42,9 years of age, with normal cranium CT finding, craniogram and fundus. They were divided in two groups: Group A--21 person who prophylactically took a daily dosage of 400 mg Carbamezepin and during acute pain attacks Naproksen; and group B--19 persons who prophylactically took daily dosage of 400 mg Carbamezepin. EEG test was done twice--before and after the medication, in order to check the concentration of different waves in the EEG in percentages. The T-test doesn't show a statistically significant difference between the alpha (p 0,719), beta 1 (p 0,865), beta 2 (p 0,710), theta (p 0,867) and delta (p 0,272) waves for the group A and for the group B alpha (p 0,996), beta 1 (p 0,920), beta 2 (p 0,826), theta (p 0,324) and delta (p 0,820) waves, on the significance level p 0,05 in the EEG at the beginning and the EEG at the end of the examination. The t-test does show a statistically significant difference between the intensity, frequency, duration and relief of pain at the beginning and at the end of the examination for both test groups. CONCLUSION Carbamazepin and Paracetamol do not cause changes in the EEG nor in the quantity in percentage terms of concentration of different waves in the control EEG in patients with vascular headaches. Statistically Carbamazepin and Paracetamol significantly change characteristics of pain and can be used for migraine treatment and prophylaxis.

Gall disease and gall tract diseases, except anamnesis characteristics, physical examination and biochemical findings, require application of modern visual technology which with its high sensitivity and specificity allows quick, accurate and verifiable diagnosis and favorable outcome of disease, a false positive and false negative findings are reduced to a very low percentage. Data from the literature shows the sensitivity of Transabdominal ultrasound (TUS) up to 90% and specificity from 20 to 85%, while CT shows sensitivity up to 87% and specificity up to 90%. In our research, which included 366 patients with gall and gall tract pathology and 147 of them were treated surgically, shows TUS sensitivity up to 87.5%, but the low specificity of 28.5%, mainly caused by a large number of patients with gall tract pathology. CT shows high sensitivity of 100% and 100% specificity, which diverge from data from the literature because CT was done after TUS and with the selection of diagnostically complicated cases. In all these complicated cases surgical findings have confirmed CT diagnosis. From this we can conclude that the application of image technology allows fast and accurate diagnostic and treatment of gall and gall tracts.

AIM AND PURPOSE Estimation of hematological laboratory effectiveness usage in family medicine, by an assessment of appropriate testing indications and efficiency of testing interpretation. METHODS For each patient who was sent to hematological testing, physicians fulfilled the questionnaire. Data gathered was used for computation of diagnostic technology operational characteristics: sensitivity, specificity, predictive values, clinical effectiveness, diagnostic odds ratio and error odds ratio. The data were served for interpretation assessment of testing results. For assessment of indications for hematological testing accuracy setting we used: the number needles (unwanted) testing according to operating diagnosis, number of confirmed operating diagnosis, and number of cases in which testing influence to therapy selection or health improving. RESULTS The results have shown sensitivity value of 0.88, specificity value of 0.97, positive predictive value of 0.98, and negative predictive value of 0.85. Effectiveness of diagnostic technology was 0.92, diagnostic odds ratio was 238 and error odds ratio was 0.2. Unwanted haematological testing has noted in 37.3% cases, but pre-test diagnosis had confirmed in 51.8% cases. The testing contribution to improving health status of patients was noted in 57.8% of cases. CONCLUSION The results have shown high level of accuracy, effectiveness and diagnostic odds ratio. However, poor assessment of testing indications has shown poor contribution to improving of patient health status.