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Publikacije (5)

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F. Omeragić, A. Tulumović, E. Iljazović, A. Adžajlić, A. Šuko, Larisa Mešić-Đogic, V. Perendija

Introduction   Pap smear, the main tool of cervical cancer screening is not always available, but some patients are in urgent need for proper diagnostic. Aim of this article was to investigate accuracy of colposcopy for detection of squamous intraepithelial lesions of low or high grade (LGSIL, HGSIL) and to promote colposcopy as useful tool for detection of patients in need for immediate further diagnostics.  Methods Prospective multicentric study performed in BH 95% CI = 42.024 to 5713.304).  HGSIL was confirmed in 27 (87%) cases by histology (CIN II /CIN III). There were no statistically significant differences between colposcopic finding and histology results (Yates-corrected χ2 = 0.33 P = .5637) Conclusions This study showed high level of correlation between colposcopy and PAP results    (63-64%) and to histology for HGSIL (87%). In absence of PAP test colposcopy could be used to select patients in need for biopsy.

F. Omeragić, A. Tulumović, H. Karahasan, Larisa Mešić Ðogić, E. Iljazović, A. Šuko, A. Brčić

AIM To investigate the ovarian cancer incidence for the period 1996-2010 in the Federation Bosnia and Herzegovina (FBandH) emphasizing that there is no official cancer database for that period. METHODS This retrospective study analyzed ovarian cancer incidence in the period 1996-2000 and an estimation of incidence for the period 2000-2010 based on this data, as well as on 2007 -2010 incidence according to the Federal Public Health Institute. RESULTS The incidence of ovarian cancer in the period 1996-2000 was 3.68-6.38/100.000. The estimate of incidence for the period 2000-2010 resulted with the rate of 14.6 at the end of the analyzed period. According to the Federal Public Health Institute, incidence for the period 2007-2010 was 11.4-12.4/100.000. CONCLUSION According to different sources incidence of ovarian cancer in the Federation BH varies from 11.4-12.4/100.000, which is lower than the incidence for Southern Europe and neighboring countries. Incidence published by the International Agency for Research on Cancer (2008) for BH (both entities) was 10.1/100.000. An increasing trend of incidence is evident too. However, in FBiH a cancer database does not exist, while the system of cancer registration does not function or operate without proper coordination. A further main task for health authorities is to establish a functional system of cancer registration and a database, which would enable a follow-up and work on prevention and early detection of ovarian cancer.

Introduction: Gynaecological and obstetric surgeries are high risk operations for the development of postoperative inflammatory complications due to the proximity of the genitourinary tract. The aim of this study was to compare the frequency of inflammatory complications in emergency or elective cases of caesarean sections as well as the frequency of complications related to the method of surgical treatment used.Methods: We analyzed inflammatory complications in 450 caesarean sections, which developed in a one year period from June 1st, 2000. to June 1st 2001. Patients were grouped according to the method of the surgery, and on emergency or elective case. Misgav Ladach or Dorfler surgical methods were used.Results: The most common inflammatory complication was wound infection and the most common risk factors for inflammatory complications were premature rupture of membranes and anemia.Conclusions: Long term use of one antibiotic was the most commonly implemented form of antibiotic prophylaxis.

E. Bašić, Hadze Kozaric, Mirza Kozaric, A. Šuko

Ovarian cancer is the sixth most common site of tumor formation in women in Federation of Bosnia and Herzegovina, entailing 5.6% of all incidence of cancer in women. According to the Public Health Institute of Federation of B&H there were 99 newly diagnosed ovarian cancer patients in 2008. Aim: The aim of this article is to present the incidence of ovarian cancer stages in women who have been treated at the Clinical Center of the University of Sarajevo in 2009. Methods: The number and type of surgical procedure was analyzed using the protocols from the Clinic of Gynecology and Obstetrics and Clinical Pathology and Cytology. Results: Surgical treatment was done in 32 patients with ovarian cancer. The most commonly diagnosed cancer is serous adenocarcinoma in 13 patients (41%), mucinous in 11 (34%), endometriod in 5 (16%), and undifferentiated adenocarcinoma in 3 patients (9%). Average age of patients was 58.1 years. According to the FIGO classification, most women who undertook surgery were in the Ia stage of the disease (13 patients, 42%). The Ib stage was diagnosed in 3 patients (9%), IIa stage in 2 (6%), and IIc in 1 (3%). In the advanced stage III of the disease there were 10 patients (31%), and in stage IV there were 3 (9%). Twenty three patients had metastatic disease. Most common sites of metastasis were omentum (12 patients, 52%), peritoneum (5, 22%), stomach (3, 12%), uterine tube (1, 4%), uterus (1, 4%), and intestines (1, 4%). Conclusion: In 2009, two thirds of diagnosed ovarian cancer was operable. Out of those patients, 40% were in the advanced stages of the disease according to the FIGO III and IV stages. Patients in stages II to IV underwent chemotherapy at Clinic of Oncology after the surgical treatment. Unfortunately, specific test for diagnosing ovarian cancer has not been found. In order to increase the survival of cancer affected women and to improve their quality of life, it is necessary to focus on the early detection of ovarian cancer.

E. Bašić, Hadze Kozaric, Mirza Kozaric, A. Šuko

UNLABELLED According to the Public Health Institute of the Federation of Bosnia and Herzegovina there were 132 newly diagnosed patients with cervical cancer in 2008. AIM The aim of this article is to present the incidence of precancerous changes on the cervix and cervical cancer as well as the incidence of the use of conization as the type of treatment for cervical patients. METHODS The number and type of surgical procedure was analyzed using the protocols from the Clinic of Gynecology and Obstetrics and Clinical Pathology and Cytology. At the Clinic of Gynecology and Obstetrics cold-knife conization with application of Sturmdorf sutures. RESULTS In 2009 at the Clinic of Gynecology and Obstetrics there were 72 newly diagnosed women with cervical cancer, out of which 16 had in situ carcinoma, 158 CIN I lesions, 64 CIN II lesions, and 46 CIN III lesions. Planocellular carcinoma was diagnosed in 59 patients (82%), cervical adenocarcinoma in 13 patients (18%). 114 patients were treated with conization with the application of Sturmdorf sutures. The most common diagnosis made with pathohistological analysis of the conization was CIN III/CIS, which was found in 48 (29%) patients. CIN II and CIN III were diagnosed in 33 (29%) and 27 (24%) patients, respectively. CONCLUSION Surgical method of treatment of precancerous changes as well as cervical cancer using the cold-knife conization with Sturmdorf sutures has shown high efficacy but with certain disadvantages such as the formation of scars, cervical stenosis, postoperative bleeding and others. Therefore, there is a need for the introduction of new protocols and newer methods of treatment. In order to decrease the number of women with precancerous changes, screening program is needed as the required part of women's health care plan as well as the introduction of HPV vaccination program.

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