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N. Angelakopoulos, S. De Luca, I. Oliveira-Santos, I. A. Ribeiro, I. Bianchi, S. Balla, H. Kış, Lourdes Gómez Jiménez et al.

The aim of this study was to assess awareness among the students of the Faculty of Dentistry of the University of Sarajevo of the occupational health risks associated with dental profession. The research was conducted among the dental students of all years of study at the Faculty of Dentistry of the University of Sarajevo, by using a tailor-made survey questionnaire. The questionnaire was completed by 446 students. Results: 92% of students believe that dentistry is a profession that involves a high level of risk for the outbreak of occupational diseases. Students believe that practicing dentistry can most often lead to various infections (70%) and vision impairments (64%), and that the most common potential causes of occupational diseases are poor positioning and incorrect body posture during work (88%) and infections (78%). When asked whether the occupational diseases among dentists are preventable, 89% of students gave an affirmative answer, and pointed to the requirement to use Personal Protection Equipment – PPE (94%) as the most important measure for the prevention of occupational diseases among dentists. The results of the survey show that the students of dentistry at the Faculty of Dentistry of the University of Sarajevo have reached a certain level of awareness of the health risks that are associated with their future profession. The students have taken a largely identical view that dentistry is a profession that involves a high level of risk for the development of occupational diseases.

Objectives The development of third molars can be helpful in dental age estimation of adolescents and in early adult period. We tested the repeatability and accuracy of the three dental age radiographic methods (Olze, Demirjian and Solari and Abramovitch) and evaluated which method is more useful. We also aimed at testing to find the correlation of estimated dental and chronological age by these three methods. Material and methods The orthopantomographs (OPGs) of 1007 individuals (8 - 25 years) were divided into two groups (cca 500 OPGs) - one group of OPGs has been presented with all four third molars, while another one was registered with third molar/s hypodontia. And all of OPGs were assessed, to verify the three methods (Olze, Demirjian and Solari and Abramovitch) for age estimation based on third molar development. Results There was a high Spearman's correlation coefficient between stages of development of wisdom tooth and chronological age of subjects by all these three methods. Conclusion We may recommend using third molars for assessing the dental age by Olze, Demirjian and Solari and Abramovitch dental method as well, on Bosnian and Herzegovinian population.

S. Špirtović-Halilović, A. Osmanović, D. Završnik, Aida Selmanagić, Selma Škrbo, Nihada Škrijelj, S. Trifunović, S. Roca et al.

Four 4-hydroxycoumarin derivatives were synthesized and the structure was confirmed by NMR spectroscopy and Mass spectrometry. Tested compounds have shown significant antimicrobial activity against Bacillus subtilis subsp. spizizenii, Bacillus cereus, Staphylococcus aureus, and Staphylococcus epidermidis, and the effect of more halogens on the benzene nucleus, as well as the combination of halogen and alkyl groups, on the antimicrobial activity, was investigated. According to the docking study, these compounds can operate simultaneously on two enzymes, amylase and gyrase (1BAG and 1KZN), which are known to play an important role in bacterial life. Obtained docking study parameters for tested compounds showed an association with the in vitro results of the antimicrobial activity of these compounds. In silico tests of molecular properties of the tested compounds showed that the compounds met Lipinski's rule of five. In this paper, the ADME parameters of tested compounds were also calculated: Caco2 (in vitro Caco2 cell permeability), HIA (human intestinal absorption), MDCK (in vitro Mandin Darby Canine Kidney (MDCK) cell permeability), TPSA (topological polar surface area), etc.

Svrha: Svrha istraživanja bila je pronaci poveznicu između eruptivnih stadija trecih maksilarnih i mandibularnih kutnjaka s lijeve i desne strane celjusti. Materijali i metode: Uzorak istraživanja ci- nilo je 529 ortopantomograma (OPG-a) – 264 (49, 9 %) pripadalo je muskom spolu, a 265 (50, 1 %) ženskom spolu u dobi između 8 i 25 godina. Sudionici su bili prema Olzeovoj metodi podijeljeni u sest dobnih skupina. Rezultati: Dobivene su visoke vrijednosti Spearmanova koeficijenta pove- zanosti između eruptivnih stadija lijevih i desnih maksilarnih i mandibularnih trecih molara. Izme- đu spolova nisu pronađene statisticki znacajne razlike u eruptivnim stadijima. Zakljucak: Prema dobivenim rezultatima za procjenu dentalne dobi u bosansko-hercegovackoj populaciji, preporu- cujemo Olzeovu metodu i trece mandibularne molare. Treba istaknuti da su moguce razvojne asi- metrije i da svaki dentalni antropolog mora biti svjestan te cinjenice. Svaka strana celjusti treba- la bi se posebno procjenjivati.

Selma Muzurović, E. Babajić, T. Masic, Rubina Smajić, Aida Selmanagic

UNLABELLED The aim of this study is to determine relationship between oral hygiene and colonisation of Candia species in oral cavity. INTRODUCTION Maintenance oral hygiene is reducing pathological agents in the mouth and preventing violation of oral health. MATERIAL AND METHODS Study included 140 patients. For oral hygiene assessement were used the dental plaque index, oral hygiene index and dental calculus index. Ph test strips were used to determine pH of saliva. For isolation of Candida species oral swabs were taken to all patients. RESULTS It was found out that pH of oral cavity does not varies notably, no matter of oral hygiene level. Candida species were identified in 28.6% respondents. The most present were Candida albicans, in 85% cases. The presence of plaque, tartar and high index oral hygiene (IOH) in patients with Candida is statistically significant. It was found that 83.4% of patients with Candida poorly maintained oral hygiene. Poor oral hygiene is associated with a significantly higher score in the presence of tartar, plaque and high IOH. In total patient's population 67% has amalgam fillings. Presence of amalgam fillings in patients with identified Candida was statistically significant. CONCLUSION This study indicates low level of oral hygiene. Correlation between presence of Candida species and poor oral hygiene was proved. Also Candida was more present among patients with amalgam fillings. Improvement of oral hygiene is necessery for oral health and health in general, as well.

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