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10. 1. 2014.
Micellar Solubilization of Carbamazepine
Aims: An important property of micelles with particular significance in pharmacy is their ability to increase the solubility of poorly soluble drugs in water thus increasing their bioavailability. It was of interest to increase the solubility of carbamazepine (CBZ) in aqueous media. Therefore, solubilization of carbamazepine (CBZ) in variety of surfactants was investigated. Study Design: In this work the solubilization of carbamazepine (CBZ) was studied in micellar solutions of different anionic and cationic surfactants.