Insulin-like growth factor-binding protein-1 ( IGFBP-1 ) in cervical secretions in women with symptoms of preterm delivery
ABSTRACT The aim of this prospective study was to investigate a value of insulin-like growth factor-binding protein-1 (IGFBP-1) in cervical secretion in women with symptoms of preterm delivery and correlate this test to the Bishop Score in prediction of a preterm delivery. The study group included 30 pregnant women with singleton pregnancy between 24 – 34 gestational weeks who were hospitalized because of a threatening preterm delivery with intact fetal membranes. A positive Actim Partus test (concentration higher than 10 μg/l) and Bishop Score higher than 4 signify a risk of the preterm delivery. The Bishop Score is a better predictor of the preterm delivery in patients with symptoms of the preterm delivery.