Ketoacidosis at Onset of Type 1 Diabetes Mellitus in Children in Bosnia and Herzegovina: Frequency and Clinical Presentation
Type 1 diabetes mellitus (DM1) is diagnosed in children worldwide in between 15% and 67% of cases at the stage of diabetic ketoacidosis (DKA). This complication of new onset DM1 is characterized by hyperglycemia (blood glucose >11 mmol/1), acidosis (venous pH <7.30 and/or bicarbonate <15 mmol/1) and glycosuria, ketonuria and ketonemia. In Bosnia and Herzegovina, data on DKA at DM1 onset are not yet available. The aims of the present study were to describe the frequency and patterns of the clinical and laboratory characteristics of DKA at onset of DM1 in children who were hospitalized at the Department of Pediatrics in Tuzla, Bosnia and Herzegovina, during the past 16 years.