[Stimulation of labour with premature rupture of membranes].

INTRODUCTION The objective is to examine the efficiency of the application of prostaglandins (PgE2) in labours with the complications of premature rupture of membranes (PRM) for the purpose of their more frequent use. STUDY DESIGN Two groups of term labours with the complications of PRM were observed in Gynaecology and Obstetric Clinic in Tuzla, in 2002. In the examination group No=59 (46.82%), we used vaginal suppositories prostin E2 (3 mg) for stimulation of labour. In the second group of pregnant women, No=67 (53.17%) we used oxytocin for stimulation. The following was observed: the age of pregnant women, parity, Bishop score, latent period (time from application of the medicine until delivery), manner in which the labour was ended, birth weight, Apgar score after the first and the fifth minute, incidence of complications (infections and bleeding) in the period of confinement/puerperium). RESULTS PgE2 were applied in pregnancies in earlier gesational age (37.31 versus 39.13), more often in nulliparous women (86.46%), in the case of immature cervix (Bishop score 3.70 versus 5.95). There were 80.45% successful stimulation, the same incidence of Cesarean sections, with no difference in the condition of newborns at birth (average Apgar score in the group with Pg 8.63), without difference in the incidence of complications in the confinement puerperium. In the group with Pg, there was a small percentage of infections, although the latent period was in 5.67% pregnancies longer than 24 hours. CONCLUSION The application of PgE2 vaginal suppositories for maturing and stimulation of labour is a modern, efficient and easy to use method in obstetrics which is very acceptable.