EP675 Pregnancy after fertility sparing treatment of embrional carcinoma figo III C
Introduction/Background Malignant ovarian germ cell tumors (MOGCTs) account for 2–5% of all ovarian cancers and among them pure embryonal cell cancer is rare condition.1 2 3 4 Methodology Aim: To show successful pregnancy after unilateral salpingooopherectomy and chemotherapy in a girl with embryonal carcinoma of ovary (ECO). Results Case report: A 11 year old girl presented in January 2008. with pain in abdomen and abdominal wall hardness. CT revealed a 12 × 10 × 11 cm heterodense mass. Right sided salpingoophorectomy, omentectomy, biopsy left sided ovary was done. Histopathology examination and immunohistochemistry revealed embryonal cell cancer of ovary. Patient had FIGO stage III c disease. After the surgical removal of the tumour, the patient underwent six cycles of adjuvant chemotherapy with bleomycin, etoposide and cisplatin. Within eight year after the completion of chemotherapy she conceived spontaneously. At 39th gestational week, laparotomy as well as a C-section was done and the patient was managed successfully in giving birth to a healthy female baby (birth weight and lenth 3,430 gm/53 cm, Apgar score: 9/9). At the last follow-up visit (May 5, 2018), all the tumor markers were negative, and the control MRI and ultrasound examinations did not reveal tumor recurrence or pathological lymph nodes. Conclusion Fertility preservation surgery followed by chemotherapy may be considered as standard care of treatment in embryonal carcinoma of ovary in young girls, who want to retain fertility. Disclosure Nothing to disclose.