In vitro fl uoride release from a diff erent kind of conventional and resin modifi ed glass-ionomer cements

Fluoride release is important characteristic of glass-ionomer cements. Quantity of fl uoride ions released from the glass-ionomer cements has major importance in defi nition of their biological activity. Th e objectives of this study were to defi ne the quantity of fl uoride ions released from the experimental glass-ionomer cements and to defi ne the eff ect of fl uoride ions released from the experimental glass-ionomer cements on their cytotoxicity. Concentrations of the fl uoride ions released in the evaluated glass-ionomer cements were measured indirectly, by the fl uoride-selective WTW, F electrode potential, combined with reference R/D electrode. Statistical analyses of F-ion concentrations released by all glass-ionomers evaluated at two time points, after  and after  hours, show statistically higher fl uoride releases from RMGICs: Vitrebond, Fuji II LC and Fuji Plus, when compared to conventional glass-ionomer cements: Fuji Triage, Fuji IX GP Fast and Ketac Silver, both after  and after  hours. Correlation coeffi cient between concentrations of fl uoride ion released by evaluated glass-ionomer cements and cytotoxic response of UMR- osteoblast cell-line are relatively high, but do not reach levels of biological signifi cance. Correlation between concentrations of fl uoride ion released and cytotoxic response of NIHT mouse fi broblast cell line after  hours is high, positive and statistically signifi cant for conventional GICs, Fuji Triage and Fuji IX GP Fast, and RMGIC, Fuji II LC. Statistically signifi cant Correlation coeffi cient between concentrations of fl uoride ion released and cytotoxic response of NIHT cell line after  hours is defi ned for RMGIC Fuji II LC only. ©  Association of Basic Medical Sciences of FB&H. All rights reserved