[Effect of the pregnant woman's socioeconomic status on serum immunoglobulin levels in the neonate].

Serum concentration of immunoglobulin G (IgG) of new-born child, at the birth, which reach the concentration of an adult persons, are the origin of mother and transferred by active and passive transport, by placenta. Immunoglobulin M (IgM) and Immunoglobulin A (IgA), do not pass the placenta because of their structure. Main condition for passing of IgG are normal period of pregnancy and regular function of placenta. Social-economic status (SES), and also immunologic status of a pregnant woman, an affect on the immunological status of new-born child. 120 pregnant woman and 120 of their new-born children were studied. Pregnant woman were at age of 18-34 years, and during the pregnancy they were healthy. Gestational age of new-born children was from 38 to 40 weeks, and birth weight was from 3000 grams to 4000 grams. The new-born children were from monofertile pregnancies, without visible anomalies and signs of intrauterine suffer. They were divided into 2 groups, 60 patients in every group, in comparison of SES families of a mother, in which she lived during the pregnancy. From every new-born child at the birth, from the blood of a navel it was determined the concentration of serum IgG, IgM and IgA. The values of IgG from the group with bad SES, were significantly lower (p < 0.001), in compare with a group with good SES. There was not statistically important difference between middle values of mentioned parameters among the different sex in the studied groups. Concentrations of IgM in new-born children were below the level of determination or just above it, so they could not be analysed anymore. Immunoglobulins A were not found in both groups, A and B groups.