One of the most significant health issues is the disorders of mood according to the fact that they have a significant effect on the quality of life of the patients, their families, their working and wider social surroundings. According to the World Health Organization, mood disorders are the fourth cause of morbidity and mortality with a tendency to move to the second place by the 2020. The prediction of higher number of patients diagnosed with depression in the future comes from the facts that the main factor of risk, like stress, is in constant rise. Furthermore, the demographic image (ageing of the population) is changing, associated with the effect of comorbidity of depression, also attributed with increase of the number of genetically predisposed patients with this mood disorder. The aim of this study is to define, describe and question the role of pharmacists in the treatment of patients suffering from depression. Therefore, we measured the impact of pharmaceutical care on significant parameters in treatment of depression due to the selection of appropriate therapy according to the guidelines, adherence of the patient, quality of life, work capability, anxiety, side effects and interactions with other medicines.

Introduction: Tonsillopharyngitis (sore throat) is a common disease mainly related to the seasonal common cold. To relieve unpleasant symptoms and discomfort of acute tonsillopharyngitis associated with common cold, patients usually take some non-prescription drugs. The aim: The primary aim of this study was to assess subjective determinations of the efficacy and the safety/tolerability of an oral spray comprising a combination of lysozyme chloride and cetylpyridinium chloride in those patients. Material and methods: The study involved 1727 patients with tonsillopharyngitis associated with common cold and treated with the studied drug, in the period from December 2014 through March 2015. Results: In total, 95% of patients rated the studied drug to be well, very well and excellently effective. In 32% of patients, the symptoms were relieved 10 minutes after the application of the spray. Significant correlations were found between the two subjective assessments of the drug efficiency with the total of 74.11% (95% CI: 73.41, 77.47%) of patients who said that the feeling of pain in the throat completely disappeared after the drug administration, evaluated the impact/effect of the drug was very good or good (Pearson Chi Square=391.401, p<0.001). The effectiveness was significantly better in patients with up to two episodes of common cold a year (Pearson Chi Square=6.101; p=0.014). The studied drug was rated to be well, very well and excellently tolerated by 97% of patients. Conclusion: According to patients’ subjective assessment, the combination of lysozyme chloride and cetylpyridinium chloride in a formulation of spray can quickly, efficiently and safely resolve the symptoms of acute tonsillopharyngitis associated with common cold.