Introduction: Psoriasis is a chronic disease. Research shows the emergence of harmful habits such as cigarette smoking and alcohol consumption in people with psoriasis. Aim: The aim of this study was to determine the frequency of habits, cigarette smoking and alcohol consumption in patients with psoriasis, sexual distribution, and the relationship of habits with the severity of the disease. Methods: The prospective study included 129 subjects with psoriasis, of which 67 or 51,94% were women and 62 or 48,06% were men. Results: The frequency of cigarette smoking was 41,09%, alcohol consumption 24,80%. The gender distribution of cigarette smoking was: 35,82% of women and 46,77% of men smoked cigarettes. The gender distribution of alcohol consumption is: women 5,97% and men 45,16%. The severity of psoriasis, that is PASI score and cigarette smoking were statistically significantly related (r=0,63), and PASI score and alcohol consumption were not statistically significantly related (r=0,32). Conclusion: Cigarette smoking and alcohol consumption are present in psoriasis sufferers, cigarette smoking is associated with disease severity, and alcohol consumption is not. It takes knowledge of the habits of people with psoriasis and a multidisciplinary approach to get rid of harmful habits.

Background: Psoriasis is a chronic incurable disease, and patients develop associated diseases such as obesity, diabetes, high blood pressure, dyslipidemia. Objective: The aim of the study is to determine the frequency of comorbidities (obesity, diabetes, dyslipidemia, high blood pressure) in men with psoriasis, and the relationship between the duration of psoriasis and the occurrence of comorbidities. Methods: A prospective study was conducted and included 88 male subjects, mean age 52,70 (SD=± 14,05) years, mean psoriasis duration 15,13 (SD=±12,43) years. Results: The incidence of obesity was 30,68%, high blood pressure 29,55%, dyslipidemia 22,73%, diabetes 13,64%. There was a weak correlation between the duration of psoriasis and the occurrence of obesity (r=0,11), dyslipidemia (r=0,18), diabetes (r=0,01), and high blood pressure (r=-0,02). Conclusion: Comorbidities occur in men with psoriasis, and their occurrence is not related to the duration of the disease.

Introduction: Changes in the skin can occur as part of a diabetic, metabolic disorder or diabetic complications. Studies have shown that diabetes has an extremely strong negative impact on quality of life, especially diabetes with complications. Aim: Examine the impact of skin changes in patients with type 2 diabetes mellitus on quality of life. Methods: A prospective study analysed the quality of life in 200 respondents with type 2 diabetes mellitus which had diabetes-related skin changes. Subjects were divided into four groups according to the type of skin changes associated with diabetes mellitus. Group 1 consisted of patients which had skin changes with a greater or lesser association with diabetes mellitus, group 2 patients with infections, group 3 patients with cutaneous manifestations of diabetic complications and group 4 patients with allergic reactions to antidiabetic therapy. Quality of life assessment was performed using the Skindex-29 questionnaire, and the Nijsten categorization was used to assess the impact of skin changes in patients with type 2 diabetes mellitus on quality of life. Results: There were (51.95%) respondents in group 1, group 2 (24.02%), group 3 (22.22%) and group 4 (1.8%) respondents. In the scale of emotions in 84 respondents (43.0%) the impact on quality of life was serious, in the scale of symptoms in 96 (48%) was moderate, and in the scale of social and physical functioning 106 (55%) also had a moderate impact on quality of life, as well as in the total score of 94 respondents (47%). There was a statistically significant difference in the scale of social and physical functioning in the presence of skin changes in group 1 (x2 = 7.95; df = 3, p = 0.045) and group 3 (x2 = 12.48, df = 3; p = 0.006), and in the total score of Skindex-29 when it comes to changes in the skin of group 3 (x2 = 7.26, df = 3, p = 0.05). Conclusion: the quality of life in patients with type 2 diabetes mellitus which have skin changes is significantly reduced.

Psorijaza je kronična kožna bolest koja se manifestira eritematoznim plakovima prekrivenim bjeličastim ljuskama. Pretpostavlja se da od psorijaze u svijetu boluje 120-180 milijuna ljudi (1). Etiologija je nepoznata, ali se smatra da je psorijaza multifaktorski uzrokovana bolest koja nastaje složenom i dinamičnom interakcijom genetskih, okolinskih i imunoloških faktora. Stres se smatra najvažnijim i najjačim provocirajućim faktorom, koji utječe na pojavu, kao i na pogoršanje postojeće psorijaze. Istraživanja su pokazala da je psihološki stres prethodio pojavi psorijaze u 44 %, a doveo do pogoršanja psorijaze u 88 % bolesnika (2,3). Saznanje da boluju od psorijaze, njena neizliječivost, kronicitet i nepredvidljivost, praćena pogoršanjima, raširenost i prisutnost promjena na vidljivim dijelovima tijela, mogućnost pojave psorijaze i u mlađih osoba, kao i razvoj pridruženih bolesti utječu na i zičko i psihičko zdravlje, radnu sposobnost i produktivnost, društvene aktivnosti i uopće na kvalitetu i način života oboljelih (4). Psorijaza se, osim sa svojim dobro poznatim i najčešćim pratiteljem, psorijatičnim artritisom, često pojavljuje udružena i s drugim bolesnim stanjima, tzv. komorbiditetima, od kojih su najprominentniji kardiovaskularni i metabolički komorbiditet koji su najčešći faktori pogoršanja kvalitete života i skraćenja životnog vijeka pacijenata sa psorijazom (5). U odnosu na opću populaciju oboljeli od psorijaze imaju veću učestalost metaboličkog sindroma, a bolesnici s težim oblikom psorijaze imaju veći izgled za razvoj metaboličkog sindroma u odnosu na one s blažim oblikom KVALITETA ŽIVOTA OBOLJELIH OD PSORIJAZE U ODNOSU NA TEŽINU KLINIČKE SLIKE I PRISUTNOST KOMORBIDITETA

Introduction: Psoriasis is a chronic skin ailment, which can be connected with other ailments including dyslipidemia. Examinees and methods: Research included 70 patients affected by psoriasis. Both genders, above 18 years of age. Average age of the respondents was 47.14 (SD= ±15.41), which consisted of 36 men (51.43%) and 34 women (48.57%). The average duration of psoriasis was 15.52 (SD= ±12.54) years. Results: Frequency of dyslipidemia on those affected by psoriasis was 62.85%. Most often it was hypertriglyceridemia (39%) and hypertriglyceridemia with a lowered value of HDL (36%), average age of those affected by psoriasis with dyslipidemia was 48.76 years (SD= ±14.72), and the average duration of the basic disease was 16.15 years (SD= ±12.63), the average values of the PASI score were 16.65. Increase in values of PASI score and dyslipidemia were statistically significantly connected (r=0.41; p=0.0001). Conclusion: Psoriasis is connected with dyslipidemia.

Introduction: Psoriasis is a chronic skin ailment which can be connected with an increased occurrence of other illnesses, including high blood pressure. Examinees and methods: A prospective study has been conducted which included 70 patients affected by psoriasis, both genders, older than 18 years. Average age being 47,14 (SD= ±15,41) years, from that there were 36 men or 51,43 and 34 women or 48,57%. Average duration of psoriasis was 15,52 (SD=±12,54) years. Results: Frequency of high blood pressure in those affected by psoriasis was 54,28%. Average age of the patients with psoriasis and high blood pressure was 53,79 year (SD=±14,15) and average duration of psoriasis was 17,19 years (SD=±13,51). Average values of PASI score were 16,65. Increase in values of PASI score and high blood pressure were statistically highly related (r=0,36, p=0,0001). Conclusion: Psoriasis was related to high blood pressure and there was a correlation between the severity of psoriasis and high blood pressure.