European Society of Cardiology (ESC) National Society Cardiovascular Journals (NSCJs) are high-quality biomedical journals focused on cardiovascular diseases. The Editors’ Network of the ESC devises editorial initiatives aimed at improving the scientific quality and diffusion of NSCJ. In this article we will discuss on the importance of the Internet, electronic editions and open access strategies on scientific publishing. Finally, we will propose a new editorial initiative based on a novel electronic tool on the ESC web-page that may further help to increase the dissemination of contents and visibility of NSCJs. © 2013 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L. All rights
Clopidogrel is a thienopyridine that irreversibly inhibits platelet P2Y12 receptors and adenosine diphosphate (ADP) mediated platelet aggregation. It is a prodrug that requires activation in the liver by cytochrome P450 enzymes (CYP3A4, CYP3A5, CYP1A2, CYP2C9, CYP2C19, and/or CYP2B6) . Dual antiplatelet therapy with clopidogrel and aspirin has become the mainstay of treatment of patients with acute coronary syndromes undergoing percutaneous coronary intervention .
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