BACKGROUND/AIM Speech motor mechanisms play a crucial role in the process of demutization, due to the fact that they cover all the elements of the successive development of spech production movements leading to speech formation (so-called kinesthesia in speach). The aim of this study was to estimate the impact of perceptual motor actions on the cognitive process of reading in 130 students in regular schools and schools for the deaf and hard-of-hearing children in the Republic of Serbia. METHODS Kostić and Vladisavljević test consisted of the ten levels weight was used for the assessment of reading speed. To assess understanding of text read by verbal responses, we used three-dimensional adapted reading test of Helene Sax. RESULTS The triage-articulation test for assessing reading speed (Kostié and Vladisavljević's test according to the weight of ten levels, revealed that students in regular schools statistically significantly faster read texts as compared to the deaf students. The results of the three-dimensional adapted reading test of Helena Sax, show that the words learned by deaf children exist in isolation in their mind, i.e., if there is no standard of acoustic performance for graphic image, in deaf child every word, printed or written, is just the sum of letters without meaning. CONCLUSION There is a significant difference in text reading speed and its understanding among the children who hear and the deaf and hard-of-hearing children. It is essential that in deaf and heard-of-hearing children education, apart from the development of speech, parallelly use the concept of semantic processing in order to get each word by the fullness of its content and the possibility of expanding its meaning in a variety of assets.

BACKGROUND Subjects that spend more time working on computers or watching television could have a higher body mass index. AIM To assess the relationship between time spent in front of a screen and studying, body mass index (BMI), smoking, and sleep duration among university students. MATERIAL AND METHODS A cross-sectional study of 734 randomly selected students aged 21 ± 2 years (450 females) that responded an anonymous, structured questionnaire about time spent watching television or in front of a computer, time spent studying, number of daily hours of sleep, smoking habits and number of daily meals. Body mass index was also calculated for all subjects RESULTS Among males, the number of daily sleep hours, time spent working with computers and number of daily meals were significantly higher and time spent studying was significantly lower than females. Nonsmokers ate a significantly higher number of meals and spent less time watching television. No association was observed between time spent in front of a screen and number of sleep hours of body mass index. CONCLUSIONS Men and smokers spend more time working in computers. There is no association between body mass index and time spent in front of screens.

<p>Skin lesions have a strong influence on the mental health. Literature indicates the complex interrelationships between psychosocial factors and psoriasis, which substantially reduce the quality of life of these patients. These interrelationships are based on numerous interactions that exist between the immune, nervous and endocrine systems and they are the basis of interactions that exist between mental and somatic health and the environment. Psychodermatology was developed as a new interdisciplinary field, a connection between psychiatry and dermatology. More than just cosmetic disfigurement, psoriasis is associated with various psychopathological problems that may have an impact on patients, their families and society. Numerous psychological disturbances occur in patients with psoriasis. Also, a significant psychiatric comorbidity was found in patients with psoriasis. Exacerbation of psoriasis leads to a deterioration of mental health. The treatment of psoriasis requires an interdisciplinary approach of a dermatologist and a psychiatrist. Various forms of psychological interventions have been proposed as a potentially useful addition to a standard pharmacological treatment of psoriasis.&nbsp;</p>

Prezentovana dostignuca u istraživanju moždanih funkcija potvrđuju ekspanziju uspesnih neuroradioloskih tehnika, ali su istovremeno i izazov da se razvijaju savrsenije tehnike kojima bi se moždana aktivnost jos jasnije osvetlila.

Fumagillin is an antibiotic derived from the fungus Aspergillus fumigatus. It has been used successfully for the treatment of intestinal microsporidiosis in HIV-positive humans, as well as in those suffering from intestinal amebiasis and microsporidial keratoconjunctivitis. In veterinary medicine it is approved for the treatment of microsporidiosis in bees and fish. In this research fumagillin was tested for the ability to provoke chromosomal aberrations in mouse bone marrow cells. BALB/c mice were administered fumagillin by gastric probe in doses of 5, 10 and 20 mg/kg b.w. Water-sugary syrup was the negative and cyclophosphamide (15 mg/kg b.w.) the positive control. Significantly increased frequencies (p<0.01 or p<0.001) of numerical chromosomal aberrations (aneuploidies and poliploidies) was observed both in the medium (10 mg/kg b.w.) and the highest (20 mg/kg b.w.) dose of fumagillin. Structural chromosomal aberrations (gaps, breaks and insertions) were noticeably more frequent in comparison to negative control only in the highest experimental dose of dycikloheksilamine. These results clearly showed that fumagillin in concetrations 10 and 20 mg/kg b.w. had a genotoxic potential in vivo.

An experiment was performed under in vivo conditions on bone marrow cells of Wistar rats. The following doses of levamisole hydrochloride were tested: a therapeutic dose of 2.2 mg/kg bm, a dose of 4.4 mg/kg bm, LD50 -25% mg/kg bm, and LD50 -75% mg/kg bm. We followed the effect of levamisole hydrochloride on kinetics of the cell cycle and the appearance of structural and numeric changes in chromosomes in bone marrow cells. The therapeutic dose of levamisole of 2.2 mg/kg bm exhibited a capability to increase mitotic activity in the observed cells, thus confirming knowledge of the immunostimulative effect of this dose of the medicine under in vivo conditions. The other tested doses of levamisole in this experiment, observed in comparison with the control group, had an opposite effect, namely, they caused a reduction in the mitotic activity of bone marrow cells. All the examined doses in vivo exhibited the ability to induce numeric (aneuploid and polyploid) and structural (lesions, breaks and insertions) chromosomal aberrations. It can be concluded on the grounds of these findings that the examined doses have a genotoxic effect.