Summary Background: Good glycoregulation at patients with diabetes mellitus is essential for prevention of many complications, including those in oral cavity. Results of numerous studies indicate that xerostomia and neurosensory oral disorders are present in type 2 diabetics. A review of the literature shows contradictory results about prevalence of oral mucosal lesions in diabetics. The aim of this study was to evaluate the presence of xerostomia, neurosensory disorders and mucosal lesions in oral cavity of type 2 diabetics. Material and Methods: This study involved 90 adults, 60 with type 2 diabetes and 30 healthy subjects, aged 45-65 years. With regard to value of HbA1c level diabetics were divided into two groups: 30 subjects with satisfactory glycoregulation (HbA1c<9%) and 30 subjects with poor glycoregulation (HbA1c≥9%). All patients recruited into the study completed a questionnaire that included their demographic, medical and oral health data. Clinical examination of the oral mucosa was performed by a single examiner. Results: In relation to the presence of xerostomia and dysgeusia between satisfactory controlled diabetics and healthy subjects a significant difference was observed (p<0.05). Compared with healthy subjects, poor controlled diabetics had significantly higher presence of xerostomia (p<0.001) and neurosensory disoders (p<0.05). A higher prevalence of oral mucosal lesions was found in poor controlled diabetics, but significant difference between groups was not observed (p>0.05). A significant positive correlation was revealed between smoking and glossodynia as well as smoking and glossopyrosis (p>0.05). Conclusion: Glycemic control level seems to influence the susceptibility of type 2 diabetics to xerostomia and neurosensory disorders. Less clear is whether diabetes are corellated to oral mucosal lesions.

Summary Introduction Local therapy of denture stomatitis (DS) associated with Candida species fungi infection usually involves the application of nystatin and miconazole. Due to the fact that these drugs may be less efficient against biofilm and possible resistance development, a new approach in the treatment includes the use of antiseptic agents. The aim of the study was to compare clinical and microbiological therapeutic outcomes of antiseptic solution Listerine® and Daktanol® antifungal oral gel in the treatment of DS associated with Candida species fungi. Material and Methods The study included 30 patients affected by DS, divided into the two treatment groups, control group (n=15) treated by Daktanol® gel and experimental group (n=15) treated by the antiseptic solution Listerine®. Successful treatment was evaluated based on palatal mucosa inflammation reduction classified according to the Newton classification and the difference in the number of fungal colony- forming units (CFU) isolated by smears before and after the treatment that lasted 14 days. Results Reduction in inflammation intensity and fungal CFU number on palatal mucosa (p<0,01) as well as on denture base (p<0,01) were observed in both groups of subjects after the treatment. Conclusion Antiseptic solution Listerine® and Daktanol® antifungal gel both reduced palatal mucosal inflammation and CFU number of fungi in mouth without significant differences among them. CFU number of fungi isolated from denture base was significantly lower after the treatment with Listerine® (p<0.05).

INTRODUCTION As a systemic disease, diabetes mellitus may lead to several complications affecting both the quality and the length of life. While periodontal disease is one of the major oral health problems in patients with diabetes, reports of an increased risk of dental caries among diabetics are controversial. OBJECTIVE The aim of this study was to investigate oral health status in patients with diabetes mellitus type 2 in relation to metabolic control of the disease. METHODS The study included 47 randomly sampled diabetics patients, divided into two groups; those with poorly controlled diabetes (glycosylated haemoglobin--HbA1c > or =9%) and those with better controlled diabetes (HbA1c < 9%). All patients completed a questionnaire about their medical and oral health. Decayed, missing, and filled teeth (DMFT) and plaque index (PI), bleeding on probing (BOP), probing pocket depth (PPD) and clinical attachment loss (CAL) were recorded. RESULTS The patients with poorly controlled diabetes had a significantly higher number of tooth caries compared to those with better controlled diabetes (6.5 +/- 4.3 vs. 4.3 +/- 2.9; p < 0.05). Of periodontal parameters, only PPD was significantly higher in the patients with poorly controlled diabetes than in those with better controlled diabetes (5.8 +/- 0.9 vs. 5.2 +/- 0.8; p < 0.05). DMFT index, PI, PPD and CAL exhibited positive correlation only with patients' age. CONCLUSION The study indicates that there is a relationship between poor control of diabetes and caries, and periodontal disease.