Logo

Publikacije (25)

Nazad
M. Koso, A. Sarac-Hadzihalilovic, S. Hansen

A previous study of ours (Koso & Hansen, 2006) indicated remarkably large decrements in neuropsychological functioning in Bosnian war veterans with posttraumatic stress syndrome (PTSD). The present study assessed attention (Sustained Attention to Response Task), executive function (Trail Making Test), and memory (Rivermead Behavioural Memory Test) in an additional group of veterans with (n = 45) or without (n = 34) PTSD. Replicating our prior study, sizeable performance decrements were observed. Furthermore, multivariate analyses revealed that (a) good verbal IQ partly buffered against the harmful effect of PTSD on more fluid cognitive functions, (b) cognitive impairment was related to PTSD symptom severity (Posttraumatic Diagnostic Scale scores) and to (c) difficulties in everyday cognitive functioning (Cognitive Failures Questionnaire scores).

Ivanka Madjar-Simic, Adnana Talić-Tanović, Z. Hadziahmetovic, A. Sarac-Hadzihalilovic

Introduction: Supracondylar humerus fractures are the most common fractures of the humerus at the elbow in children. The key role belongs to the age and immaturity of the humerus region. Treatment, even today represents the problem of bone and joint surgery. Gartland classification divides these fractures into four types. Analysis of radiographic parameters will serve as an indicator for treatment selection. Goal: To demonstrate the role of radiographic evaluation by measurement of default radiographic parameters and indicate the choice of treatment for supracondylar fractures of type I and II by Gartland. Material and methods: The study included 60 children aged 4-14 years, divided into two groups, first with initial radiographic analysis and the second one without radiographic analysis. All were treated at the Primary Health Care Center Novi Travnik and Nova Bila Hospital from 2009 to 2011. Analysis was performed using methods of descriptive statistics to calculate the mean and standard deviation, Student’s t-test and Chi-square test. Results: In patients from first group hospitalization, immobilization duration, as well as physical treatment was shorter and more frequently surgical treatment was applied (manual reduction with K-wire fixation) with statistically significant difference (p = 0.042). Conclusion: Radiographic evaluation is one way to choose methods of fracture treatment. The incidence of complications is low, with excellent outcome of treatment and a faster return of children to their daily activities.

A. Kulenović, A. Sarac-Hadzihalilovic

Arterial vascularization of the pancreas has been investigated, as well as variation in vascularization of this organ with regard to the existence of age differences. Aim of the investigation was to establish differences, if any, in newborns pancreas vascularization since diseases invading this organ in newborns have increased recently at this particular age. Injection-corrosion method was used on pancreas arteries and their variations. Twenty-four human pancreas specimens were used for this purpose consisting of 24 cadaver organs aged between 45 and 65, and 12 pancreases of still-born babies. Comparison of the findings has shown that there was no difference in the number, ramification pattern and arterial course between the two experimental groups of organs; all possible blood vessel variations were most probably the result of developmental processes which occur during early stages of intrauterine development.

1. 9. 2008.
0
F. Aksu, H. Topacoglu, C. Arman, Aytul Atac, S. Tetik, A. Hasanović, A. Kulenović, Z. Mornjaković et al.

A. Sarac-Hadzihalilovic, A. Kulenović, A. Kučukalić

The aim of this study was to analyze cognitive dysfunction in PTSD. The testing included 79 Bosnian Army veterans, who participated in Bosnian war from 1992 to 1995. Out of 79 tested war veterans, 45 of developed PTSD while 34 did not. The veterans without PTSD where included in the control group. All the war veterans were of the same education level (secondary education) and between 30 and 50 years of age. Rivermead Behavioral Memory Test - RBMT was applied to all the subjects. The test was originally developed for the purpose of everyday memory problems identification. Clear goal of the 10 RBMT subtests is simulation of everyday life situations. PTSD group achieved significantly lower results than the control group. Results of the total score showed highly significant difference between PTSD and control group. Value of the t-test is t=10,056 with significance level of p<0,001. The same conclusion stands for any RBMT subtest. Numerous psychological studies on PTSD patients show more prominent psychological deficit in war veterans. Our study clearly confirms that finding.

The goal of this work was to analyze asymmetry of hippocampal formation in PTSD patients. The objects of the analysis were 10 MRI scans of patients with PTSD with established cognitive function damage. MRI scans were obtained using MAGNET IMPACT SIEMENS 1,0 TESLA in T1 and T2 relaxation. The measurement of hippocampal formation dimensions, and comparisons between the right and the left side were done using evaluate - distance program on the MRI instrument of the Institute of Radiology at Sarajevo Clinics Center. We tested 20 patients with PTSD 49,9 years of average age with standard deviation of 4,62 years. Based on the analysis of our results regarding the size of hippocampal formation in all the three projections (axial, coronal and sagital), in the group of patients with PTSD, we can the make the following observations: 1. In axial slice the length of hippocampal formation measured on the left and right side is significantly asymmetric in all patients. In the sagital slice, the hippocampal formation measured on the left side is in many cases longer than in the right - 50 %. In coronal slice no significant differences were found in the proportion of patients according to symmetry/asymmetry of hippocampal formation width on the left and right. 2. The difference in average size of hippocampal formation between the left and right side measured in axial and coronal slices is not statistically significant, but it is significant in sagitall slice. So, the results of this new research, showed smaller hippocampal dimensions in PTSD as measured using MRI. We have to be careful about what projection we are refusing to as being watched hippocampal formation because the results will depend on that. We suggest that future studies be done in more projections because of the importance of statistically significant conclusions. MRI - volumetric measurements have their value.

A. Sarac-Hadzihalilovic, F. Dilberović, A. Kučukalić

Lobus limbicus is an anatomical basis for understanding the temporal epilepsy because it includes not only the focus of temporal lobe infection but of the frontal lobe as well. With it we can explain many of the phenomena accompanying epilepsy (hallucinations, the change of the effects, and so on). The goal of this assignment was to explore the asymmetry of amygdaloidal complex in the patients with complex partial attacks. The results show that the smallest number of patients with epilepsy have a symmetric (same size) amygdaloidal complex on the left side and the right. According to the asymmetry direction the difference in the number of patients with epilepsy is not statistically significant. Coefficient of asymmetry shows that the asymmetry on the left side is more frequent in men, while women have the same distribution on both sides. The greatest differences were found when considering the age factor. So, in all the three groups of evaluated data the differences in average age of patients with epilepsy according to total symm./asymm. were not statistically significant. But, the differences in average age depending on the direction of asymmetry were significant. Patients with longer amygdaloidal complex on the left side are significantly younger, both male and female (related to the axial slice, ant. - post. diameter). Thus, we propose the application of MRI technique in examining the asymmetry of the amygdaloidal complex that we used in this assignment as a template for future examinations in a sense of shedding light on the anatomical functions that underlie neuro-psychiatric dysfunctions.

20. 8. 2004.
3

The aim of this study is to determine the type of skull as well as to examine its internal appearance and configuration of skull base. Special attention is given to the direction and position of the pyramid of the temporal bone, the volume and appearance of all the three cranial fossas, and the direction and appearance of crista alaris--all of those compared to the skull type. Considering the obtained results (specially for crista alaris and middle fossa) we can ascertain outstanding independence of sphenoid bone and its parts in the formation of cranial base. Located in the middle of the skull, in front of strong pyramids transversal axis and two vertical axis, frontal crest and internal occipital crest, it by itself with her lesser wing presents an important transversal axis of cranial base. Cases in which crista alaris with its position does not follow the type of skull (in 20 % cases crista alaris does not follow skull protuberances), may probably be explained by strong and independent development of this bone, which is placed among other bones of cranial base like a peg. It also, by itself dictates form and configuration of the middle part of skull. That is also confirmed by middle fossa which, according to its position in the middle of cranial base and relation with sphenoid bone, shows significant deviation with respect to posterior fossa (follows the type of skull in 47 % cases).

Defining exact position of weak anatomic function which is find in a base of neurological and psychiatric disorder is just became the subject of intensive research interest. For this purposes it is important to implement structural and functional MRI techniques, also for further lightening and seeing subject of this work, more concretely connected to PTSD. Therefore, exactly MRI gives most sensitive volumetric measuring of hippocampal formation and amygdaloidal complex. The goal of this work was to research asymmetry of hippocampal formation and amygdaloidal complex to the PTSD patients. Results showed that at the axial slice length of hippocampal formation on the left and right side of all patients are significantly asymmetric. At the sagittal slice from the left side of hippocampal formation is in many cases longer than right about 50 %. At the coronal slice, there are no significant differences toward patient proportion according to symm./asymm. of the hippocampal formation width at the right and left side. Difference in volume average of hippocampal formation between right and left side for axial and coronal slice is not statistically significant, but it is significant for sagittal slice. In about amygdaloidal complex patients with PTSD toward symm./asymm. Amygdaloidal complex at the right and left side of axial and sagittal slice in all three measurement shows asymmetry, what is especially shown at sagittal slice. Difference in average length of amygdaloidal complex at the right and left side is not statistically significant for no one slice. Therefore, results of a new research that are used MRI, showed smaller hippocampal level at PTSD (researched by Van der Kolka 1996, Pitman 1996, Bremner et al., 1995.). Application of MRI technique in research of asymmetry of hippocampal formation and amygdaloidal complex, which we used in our research, we recommend as a template for future researches in a sense of lightening anatomic function that is a base of neuropsychiatric disorders.

Lobus limbicus is anatomical basis for explaining the temporal epilepsy because it not only includes the focus of infection of temporal lobe but also the frontal lobe, and with it we can explain many of the phenomenon's of the epilepsy (hallucinations, the change of the effects, and so on.). The goal of this assignment was to explore the asymmetry of hippocampal formation on the patients with complex partial attacks. The results show that the least number of patients with epilepsy have a symmetric (same) size of the hippocampal formation both from the left and the right side. The number is statistically significantly lower than the number of patients with epilepsy who has asymmetric (different size) hippocampal formation both from the left and the right side. By the direction of asymmetry the difference in the number of patients with epilepsy isn't statistically significant. Coefficient. of asymmetry shows that the asymmetry on the left side is more common to men, while it is distributed evenly on sides, left and right in women. Testing of significance in age differences depends on the sim./asim. of the hippocampal formation of both the right and the left side of coronal slice is a statistical significance. While with axial and sagittal slices, we have a statistical significance between a women and a man on the level of the course of asymmetry. So, the use of MRI technique in examining asymmetry of the hippocampal formation, that we used on this asymmetry, we suggest it as an template of future examinations in a sense of shedding light of the anatomical functions that is located on the basis of neuropsychiatrics dysfunctions.

Nema pronađenih rezultata, molimo da izmjenite uslove pretrage i pokušate ponovo!

Pretplatite se na novosti o BH Akademskom Imeniku

Ova stranica koristi kolačiće da bi vam pružila najbolje iskustvo

Saznaj više