<p><strong>Introduction.</strong> Inadequate postoperative analgesia can affect the functioning of almost all organ systems and significantly increase morbidity and mortality. The aim of study was to analyze and assess response of patient&rsquo;s painful sensations caused by surgical intervention in early stage of acute postoperative pain. <strong>Methods.</strong> This paper presents a prospective study that follows the reaction of the patient 24 hours postoperatively after different surgical procedures. The only criterion for patient&rsquo;s inclusion in the study was the need for elective surgical intervention. As a source of data used were medical records with complete medical documentation. <strong>Results.</strong> The study included 126 patients. The group is divided into three subgroups: I - gallbladder surgery, II - resection of the stomach and intestines, III - surgery of hernia abdominal wall. The same analgesics are ordained postoperative: noraminofenazon, and ketoprofen. The severity of pain and testing treatment effect was carried out peacefully, at regular intervals by the appropriate scale for the assessment of the strength and quality of pain. <strong>Conclusion.</strong> At the time of the need for analgesic patients on a scale of pain showed a value of 6,84 to 7,14 (VAS - visual analog scale). Homeostatic values of variables in the early postoperative period, it remained within normal values. Administration of analgesics &ldquo;at the request&rdquo; of the patient not achieved satisfactory analgesia, because the first postoperative day the patients will have a severe pain (VAS - 7).</p>