Aim: The aim of this study is to present the first total number of tested children in the Federation of Bosnia and Herzegovina and the number of children with positive sweat test. During the study we determined the number of ill children, the median age of children with cystic fibrosis, date of initial diagnosis, an average amount of chloride in the sweat. Material and methods: The study was a retrospective, conducted at the Department of Pulmonology Pediatric Clinic of University Clinical Center of Sarajevo. Results: In the period from March 2003 to December 2014, we have tested 625 children. 351 child were from Sarajevo Canton and 272 children from other cantons. Female children were more affected then male children, in the ratio of 1: 1,105. An average age of female children was 4.19±4.26 years, and the male 2.15±3.11 years. The median concentration of chloride in the sweat measured by sweat test was for male children 103.05±21.29 mmol/L, and for the female children 96.05±28.85 mmol/L. Conclusion: Most of children in Federation of Bosnia and Herzegovina have ∆F508 gene mutation. In the post-war period we started to use a sweat test. Male children tend to live longer than female children with CF.

This study is motivated by a need for consideration of both ethics and competitiveness through supply chain activities and its management. This research, fro m the perspectives of Bosnian firms' emp loyees, aims to identify the frequency and personal disturbance level of ethics and hu man rights issues, experienced supply chains and competitiveness of the local co mpanies in Bosnia and Herzegovina, how managers handle ethics and human rights issues through their business and with their emp loyees, and how code of ethics have influences in the business level. In order to exp lore these issues, we adopted a survey based study which has been conducted on 185 emp loyees of Bosnian firms fro m six different cit ies in BIH. The results main ly indicated that the emp loyees of the surveyed companies strongly believe that their companies have considered ethics while constructing their business and supply chains. They moreover assumed that their co mpanies do not have ethical problems. However, they are rated to be slightly good in their ethical considerations about customer buying behavior and competitiveness.

A case of lung abscessi has been reported in 10 years old child, boy. This lung disease is uncommon, but treatment is complex. A lung abscess is a suppurative process resulting in destruction of the pulmonary parenchyma and formation of a cavity containing purulent material. The child was already treated in the hospital in Bihac since 19.07.2004. to 04.08.2004. Lung abscess was secondary caused by staphylococcus, started as panaritium second finger. The diagnosis is generally made by roentgenographic examination when a cavity with a fluid level surrounded by alveolar infiltration is demonstrated. After a few consultations with thoracal surgeon conservative treatment was continued Vankomicin 40 days and Funzol, later Stanicid 10 days. Brronchosacopy to faciliate drainage or to obtain culture is controversial so the same wasn't done. Surgical drainage of a lung abscess is almost never indicated and resection should be considered only in a children with recurrent hemoptysis, repeated episodis of infection. Serial chest roentgenograms show gradual diminution of the abscessus over a period of several weeks during hospitalization. Last one chest X ray shows as sequely air cyst on the left side. X ray of the second finger shows osteitis of the second phalange. After 40 days the child was discharged with recommendation for follow up by thoracal surgeon next 6 months.

Group B Streptococcus (GBS) is the main ethiological agent of neonatal sepsis in the developed countries. Because of high mortality rate American College of Obstetrics and Gynaecologists and Centers for Disease Control published recommendation for prevention of neonatal GBS infection. Program recommends screening of all pregnant women for anogenital GBS infection including intrapartum treatment of pregnant women at high risk, with penicillin or ampicillin. Clindamicin or erythromicin may be used for women allergic to penicillin. Since there is no detailed informations of early-onset neonatal GBS infection in our country, we investigated its incidence in Pediatric Clinic in Sarajevo, from December 1999 (when first case of early-onset GBS infection in last decade was diagnosed) to August 2002. During that period 7 neonates with early-onset GBS infection were identified (incidence 0.52 per 1000 livebirths). Four of seven sick newborns died, 2/7 survived with severe neurological sequelae and only one female newborn survived without deficits. In the same period we registered 36 (2.4%) GBS colonised neonates out of 1530 admitted neonates. The number probably is higher because of discharge GBS colonized asymptomatic neonates from Maternity as a healthy to home. Results of this study intend the necessity of implementation guidelines for GBS prevention since early onset GBS infection is becoming as an increasing problems in our population.

IA case of Melkersson-Rosenthal syndrome with major and minor symptoms is presented. Clinical diagnosis was established on the basis of the triad: macrocheilia, lingua plicata and facial paralysis and a number of minor symptoms. The upper lip macrocheilia with palpation evident infiltrates corresponded to the diagnosis of granulomatous cheilitis of the upper lip. The upper lip was of intense red color, with the vermilion border effaced causing a marked cosmetic defect. The predominant subjective symptoms were burning and itching sensations with a reduction of movement of the lip. Clinical examination and palpation revealed three granulations enclosed by fissures. A slight exfoliation of the epithelia with serous exudate was dominant feature. The patient was admitted to the Oral Medicine Department of Dental School in Sarajevo on October 8th 1999 for macrocheilia relapses. The therapy using subcutaneous application of kenalog-40 suspension once a week in duration of five weeks showed substantial improvement. According to the prognostic criteria and the control examinations there were no relapses.