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B. Hadzić, M. Hadzic, N. Sljapić
0 1992.

[Standard histopathologic criteria in intraoperative diagnosis of thyroid gland diseases].

The objective of intraoperative histological diagnostics of thyroid gland diseases using the tissue freezing method is planning the appropriate surgical scope at the time of operation. This necessitates maximal diagnostic accuracy having in mind the fact that freezing changes the tissue structure resulting in numerous technical defects in the histological preparation. These defects can be eliminated by multiplying histomorphological criteria, accurate explanation of their significance and interdependency and by making a conclusion in the form of ex tempore diagnosis. We studied 88 cases of ex tempore diagnosed changes in the thyroid gland using 15 different morphological criteria. The adjustment of the metrics scale to arithmetic progression enabled us to use certain number of parametric tests. A universal approach along with non-parametric methods with highly significant results made it possible to evaluate histomorphological criteria which can be regularly used in intraoperative diagnostics of pathological changes in the thyroid gland.


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