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CURRENT RESEARCH TOPICS IN PHARMACY: Drug Delivery
mucoadhesion values than all nanoparticles and the mucoadhesion was positively correlated with the concentration of alkalizing agent because of the increased gelling properties. The mucoadhesive properties of the formulations were based on the use of positively charged chitosan and the formation of electrostatic interactions between the oppositely charged chitosan and mucin, resulting in superior mucosal retention [6].