Autonomous Swallow Segment Extraction Using Deep Learning in Neck-Sensor Vibratory Signals From Patients With Dysphagia

Dysphagia occurs secondary to a variety of underlying etiologies and can contribute to increased risk of adverse events such as aspiration pneumonia and premature mortality. Dysphagia is primarily diagnosed and characterized by instrumental swallowing exams such as videofluoroscopic swallowing studies. videofluoroscopic swallowing studies involve the inspection of a series of radiographic images for signs of swallowing dysfunction. Though effective, videofluoroscopic swallowing studies are only available in certain clinical settings and are not always desirable or feasible for certain patients. Because of the limitations of current instrumental swallow exams, research studies have explored the use of acceleration signals collected from neck sensors and demonstrated their potential in providing comparable radiation-free diagnostic value as videofluoroscopic swallowing studies. In this study, we used a hybrid deep convolutional recurrent neural network that can perform multi-level feature extraction (localized and across time) to annotate swallow segments automatically via multi-channel swallowing acceleration signals. In total, we used signals and videofluoroscopic swallowing study images of 3144 swallows from 248 patients with suspected dysphagia. Compared to other deep network variants, our network was superior at detecting swallow segments with an average area under the receiver operating characteristic curve value of 0.82 (95% confidence interval: 0.807-0.841), and was in agreement with up to 90% of the gold standard-labeled segments.