Myocardial infarction with non-obstructive coronary arteries-ghost hunting in cardiology-case report
Introduction: the most important factor regarding the survival of patients with non-small cell lung cancer (NSCLC) is the mediastinal lymph node status. The influence of several factors on the occurrence of N1 and N2 metastases was investigated, the most common being lung cancer, tumor size, and the degree of differentiation of tumor cells. Aim: to determine the association between the degree of tumor cells (G stage) differentiation and the presence of peritumoral lymphatic infiltration (PTLI) with the occurrence of N1 and N2 metastases in NSCLC. Materials and methods: the study included a sample of 331 patients, of all ages, both genders, who underwent a complete resection of previously diagnosed lung cancer. Surgery was performed under general anesthesia technique employing a Carlens tube, with the prior zonal exploration of mediastinal lymph nodes and/or thoracoscopic exploration of the pleural cavity. The peritumoral compartment in which lymphocytic infiltration was investigated is an area around the intratumoral compartment that includes the edge of the tumor and a width of 1 mm beyond it. Results: the most common type of lung cancer among patients in this study was adenocarcinoma, with PTLI in more than 69% of cases. There is a 3,5 times higher risk of developing N disease when there is PTLI comparing with cases when there is none. PTLI was present in 86 (37.6%) patients with N0 disease, 128 (55.9%) patients with N1 disease, and 15 (6.6%) patients with N2 disease. Conclusion: the presence of PTLI is significantly associated with the occurrence of N1 and N2 metastases in patients with NSCLC.