[The results of treatment children's Hodgkin lymphoma at pediatric clinic in Sarajevo].
UNLABELLED The aim of this study is to estimate the eficacy of citostatic and radiotherapy in treatment of Hodgkin disease (HD) on Hematology-oncology Department of Pediatric Clinic in Sarajevo (Bosnia and Herzegovina). PATIENTS AND METHODS In retrospective study we followed all patients with HD in the period of 7 years (01.01 1997-31. 12. 2004) Patients were up to 15 years old, and HD was diagnosed and treated at our Clinic. Till 2000 we used UKCCSG HD 9201 protocol treatment with combination of citotstatic and radiotherapy, and after 2000 protocol UKCCSG HD 2000 (ChlVPP / ABVD) was used for treatment HD. RESULTS We treated 24 children with HD (10 boys-41,66%, 14 girls-58,33). In 7 children (29,1%) we found II A stage of HD, in 4 children (16,6%) II B stage of HD, in 5 children (20,8%) stage III A, in 3 children (12,5%) stage III B, in 2 (8,3%) stage IV A and in 3 children (12,5%) stage IV B. In 5 patients (20,8 %) appeared relapse due to which we used more aggresive citostatic and radiotherapy, and in 3 patients (12,5%) in combination with bone marrow transplantation. One patient (4,1%) died. There are 23 children (95,8%) alive in 1st or 2nd remission phase. Secondary malignancies did not occur in any of patients. CONCLUSION Although there were significant number of patients diagnosed in high stage of HD (III and IV) the results of therapy HD on Pediatric Clinic in Sarajevo are good.