One Year Outcome of Patients with Acute Stroke and Sleep Apnea According to the Type and Localisation of Lesion

The aim of this study was to analyze one year survival outcome of the patients with sleep apnea in acute stroke in order to type and localisation of lesion. Patients and Methods: It was analyzed 110 patients with acute stroke (AS) and verified sleep apnea, treated at Department of Neurology, University Clinical Center Tuzla in the period December 2009 thorough may 2010. Acute stroke has been verified either by computerized tomography or magnetic resonance imaging of the brain. Average age was 65.13±9.27 years and it was 65 (59%) men. Number of participants with no apnea in control group was the same as well as sex distribution, with average age 64±8.69 years. Results: One year after acute stroke survived 78 (84.8%) patients out of 92 with apnea and ischemic stroke (IS). Otherwise, 13 (72.2%) patients survived out of 18 with hemorrhagic stroke (HS). Without apnea 88 (95.7%) patients who survived had IS and 16 (88.9%) HS. Survival of patients with IS and without apnea is significantly better than in patients with IS and apnea (X2=5.46, p=0.02). Survival of patients with HS with/without apnea is not significantly different. Majority (51/87.9%) of 58 patients with apnea who survived had lesions at two or more locations. Otherwise, 12 (100%) patients out of 12 without apnea who survived had lesion in frontal lobe. Survival of patients with/without apnea is not statisticaly different in order to location of lesion. Concerning the side of stroke 23 (85.5%) patients with apnea who survived had lesion(s) in left hemisphere but this difference is not significant. Patients without apnea 48 (96%) had lesion(s) at both sides. Conclusion: Survival of patients without apnea in ischemic stroke is significantly better than in patients with apnea. Survival in patients with/without apnea in hemorrhagic stroke has no statistical difference. Localization and side of lesion do not have influence on survival.