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M. Kacila, K. Schäfer, Nermir Granov, Faida Kučukalić
0 2006.

Donor Blood Products

The aim of this study is to compare the effects of colloidal cardioplegia and blood cardioplegia in patients who un- derwent cardiac surgical procedures with cardiopulmonary bypass, and to evaluate their influence on hemodilu- tion, bleeding and consumption of donor blood products in a retrospective clinical study.  male patients who underwent cardiac surgical procedure were divided into two groups:  patients were administered intermittent normotherm or mild hypotherm (°C) Calafiore blood cardioplegia with potassium chloride , ;  patients were administered one initial doses of cold Kirsch - solution followed from intermittent cold colloidal cardiople- gia using hydroxyethyl starch (HES /,). Hemoglobin values after the first dose of cardioplegia were signifi- cantly lower in the HES-group than in the Calafiore- group). After the first dose of cardioplegia platelets count was lower in the HES-group than in the Calafiore-group. Hemoglobin and hematocrit values h postoperative were lower in the HES-group than in the Calafiore-group. There was no difference in chest-drainage bleeding h and h postoperative between the groups. The consumption of donor erythrocyte concentrate and fresh frozen plasma was significantly higher in the HES-than in the Calafiore- group. The choice of either colloidal or blood cardioplegia does not influence the postoperative chest-drainage bleeding. The results suggest that high molecular colloidal cardioplegia with HES-solution is associated with higher hemodilution during and after car- diopulmonary bypass and significantly increases the consumption of donor blood products.


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