Influence of montelukast on exercise-induced asthma
Among specific forms of asthma, exercise-induced asthma (EIA) is the most common. One of the most important factors released in this form of asthma is leukotriens. The place and role of leukotrien modifiers in treating EIA is still not clearly defined. Ten children 5-15 years of age were included in this study. We followed up different lung parameters in children exposed to exertion before and after montelukast by using spirometry. All children included in the study were submitted to the prick test. Results obtained in our study showed that montelukast statistically significantly reduced lung parameters on exertion, when compared with the results obtained before it. Montelukast did not completely block EIA.