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A. Tucak, M. Sirbubalo, A. Zimmer, E. Vranić
1 2020.

Cationic nanostructured lipid carriers (cNLCs) as drug delivery systems for miRNA

Cationic NLCs represent lipid vesicles bearing cationic lipids on its surface, which leads to electrostatic interactions with negative charges of the nucleic acids such as miRNA and formation of a complex which protect the nucleic acids from the inevitable physicochemical biological impacts within the blood circulation [1]. This study aimed to develop cNLCs in order to obtain the most suitable formulation for further delivery of miRNAs.


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