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J. Oechtering, Sabine A. Schaedelin, P. Benkert, S. Müller, L. Achtnichts, J. Vehoff, G. Disanto, O. Findling, Bettina Fischer-Barnicol, A. Orleth, A. Chan, C. Pot, M. Barakovic, R. Rahmanzadeh, R. Galbusera, I. Heijnen, P. Lalive, J. Wuerfel, Suvitha Subramaniam, S. Aeschbacher, D. Conen, Y. Naegelin, A. Maceski, Stephanie Meier, Klaus Berger, H. Wiendl, T. Lincke, J. Lieb, Ö. Yaldizli, T. Sinnecker, T. Derfuss, A. Regeniter, C. Zecca, C. Gobbi, L. Kappos, C. Granziera, D. Leppert, J. Kuhle
18 31. 5. 2021.

Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis

We aimed to determine in relapsing multiple sclerosis (MS) whether intrathecal synthesis of immunoglobulin (Ig) M and IgG is associated with outcomes reflecting inflammatory activity and chronic worsening.


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