Effect of high frequency electromagnetic field on beta cells of langerhans islets in pancreas of rats
Taking into account the poor and contradictory data on the effects of high frequency electromagnetic fields on both human and animal pancreas, especially its endocrine part, this paper aims to test the animal model for morphological features of pancreas beta cells under the impact of a high frequency electromagnetic field (HF EMF) featuring 1.9 GHz,4.79 V/m, 0.24 A/m and 2.0 W/m2, for a 30-day period. The experimental animal group consisted of Wistar rats and the pancreas tissue of both control and radiated animals under went a series of standard and immunohistochemical coloring as a preparation for stereological analysis. In our radiated group, HF EMF caused an increase in the number, volume density, and nucleocytoplasmic ratio and a decrease in beta cell surface in comparison with the control animal group, all of which indicated enhanced activity. Briefly summarizing the results of this paper, we may infer that the experimental animals subjected to HF EMF suffered morphological and morphometric changes in the beta cells. As insulin, the hormone beta cells excrete, decreases glucose levels, these resultsindicate a potential diabetogenic action of HF EMF in rats. Key words: endocrine pancreas, immunohistochemistry, volume density