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S. Turajlic, L. Au, A. Fendler, S. Shepherd, K. Rzeniewicz, M. Cerrone, F. Byrne, E. Carlyle, K. Edmonds, L. D. Rosario, J. Shon, W. Haynes, B. Ward, B. Shum, W. Gordon, C. Gerard, Wenyi Xie, N. Joharatnam-Hogan, K. Young, A. Furness, L. Pickering, J. Larkin, R. Harvey, G. Kassiotis, S. Gandhi, C. Swanton, C. Fribbens, K. Wilkinson, R. Wilkinson, David Lau, N. Starling, I. Chau
1 30. 3. 2021.

Cytokine release syndrome in a patient with colorectal cancer following vaccination with BNT162b2 (tozinameran)

We present a case of cytokine release syndrome (CRS) that occurred five days after vaccination with BTN162b2 (tozinameran), an mRNA COVID-19 vaccine, in a patient with colorectal cancer on long-standing anti-PD-1 monotherapy. The CRS was evidenced by raised inflammatory markers, thrombocytopenia, elevated cytokine levels (IFN-y/IL-2R/IL-18/IL-16/IL-10), and steroid responsiveness.


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