Multy-drug resistance tuberculosis (MDR-TB) in Federation of Bosnia and Herzegovina during ten years
Multidrug-resistant tuberculosis (MDR-TB) defined as TB caused by strains of Mycobacterium tuberculosis that are resistant to at least isoniazid and rifampicin. The aim of this paper was to describe the resistance patterns of MDR-TB in FBH previously treated 121) in 2000;1184 (1054;129) in 2001; 1036 (936;100) in 2002; 1042 (951;91) in 2003; 1125 (1048; 77) in 2004; 769 (692;77) in 2005; 908 (827;81) in 2006; 951 (847;104) in 2007; 518 (471;47) in 2008; 581 (529;52) in 2009. MDR-TB among never-treated cases: 1 (0.11%) in 2000; 2 (0.19%) in 2001; 4 (0.42%) in 2002; 1 (0.10%) in 2003; 4 (0.38%) in 2004; 4 (0.57%) in 2005; 2 (0.24%) in 2006; 7 (0.82%) in 2007; 3 (0.63%) in 2008; 0 (0.0%) in 2009. MDR-TB among previously-treated cases: 2 (1.65%) in 2000; 7 (5.42%) in 2001; 9 (9.0%) in 2002; 1 (1.09%) in 2003; 6 (7.79%) in 2004; 5 (6.49%) in 2005; 3 (3.70%) in 2006; 10 (9.61%) in 2007; 9 (19.14%) in 2008; 1 (1.92%) in 2009. Conclusion: Data from FB&H show relatively low prevalences of MDR-TB during ten years.The prevalence of MDR-TB remains low at 0.57% - 0.82% among newly detected cases and 9.61% - 19.14% among previously detected cases.Recent data also indicate a further desrease in MDR-TB. This decrease may likely be the result of well implemented DOTS.Establishing reference laboratory facilities with adequate capacity to supervise DST and surveillance activities in the country is a critical step in MDR-TB control and care.