0
2004.
QSAR/QSPR OF CONDENSATION PRODUCTS OF 4-HYDROXYCOUMARIN WITH AROMATIC ALDEHYDES
QSAR/QSPR (Quantitative Structure Activity (Property)Relationships) studies provide some models for a fast search of biologically active molecules, and can be used to predict biological potential for synthesizing molecules and also for non-synthesized compounds. We used topological indicesm, selected physicochemical properties and activity for a group of derivatives of 4-hydroxycoumarin. We also investigated which topological indices are the most applicable by studyng the relationship between lipophilicity and the structure of new coumarin derivatives.