Logo
Nazad
A. Džubur Kulenović, A. Kučukalić, D. Malec
38 1. 8. 2008.

Changes in plasma lipid concentrations and risk of coronary artery disease in army veterans suffering from chronic posttraumatic stress disorder.

AIM To test the differences in serum lipid concentrations between veterans with chronic posttraumatic stress disorder (PTSD) and veterans without PTSD. METHODS We determined plasma lipid parameters and calculated risk factors for 50 veterans in the PTSD group and 50 veterans in the non-PTSD group. Trauma exposure, coping strategies, and quality of life were assessed with Life Stressor List, Manchester Short Assessment of Quality of Life Scale, and Folkman-Lazarus Coping Strategies Questionnaire. RESULTS There was no difference between the groups in the exposure to combat trauma. PTSD group had significantly lover education than non-PTSD group (10.6+/-1.8 vs 12.4+/-2.6 years, P=0.007) and lower monthly income per family member (euro67.8+/-51.3 vs euro281.9+/-208.2, P<0.001). PTSD group had significantly higher levels of all plasma lipid parameters (cholesterol: 6.54+/-1.24 vs 5.40+/-1.09 mmol/L, P<0.001; triglycerides: 2.55+/-0.68 vs 1.73+/-0.77 mmol/L, P<0.001; very low density lipoprotein-cholesterol: 1.14+/-0.32 vs 0.78+/-0.35 mmol/L, P<0.001; low density lipoprotein-cholesterol: 4.49+/-1.06 vs 3.46+/-0.93 mmol/L, P<0.001). High-density lipoprotein cholesterol concentration was significantly lower in PTSD group (0.96+/-0.18 vs 1.15+/-0.24 mmol/L, P<0.001). Established risk factor for arteriosclerosis (6.96+/-1.19 vs 4.71+/-0.88, P<0.001) and Adult Treatment Panel III ten years risk for coronary disease (19.44+/-7.27% vs 9.74+/-4.10%, P<0.001) were significantly higher in the PTSD group. Secondary traumatization was significantly more frequent in the PTSD group (3.8+/-5.7 vs 1.3+/-4.7 events; P<0.001). CONCLUSIONS Chronic PTSD is associated with dyslipidemia, leading to an increased risk of coronary artery disease. Environmental factors and coping strategies should be considered as important factors for the occurrence and persistence of PTSD.


Pretplatite se na novosti o BH Akademskom Imeniku

Ova stranica koristi kolačiće da bi vam pružila najbolje iskustvo

Saznaj više