Magnetic Resonance Imaging of T2- and Diffusion Anisotropy Using a Tiltable Receive Coil
The anisotropic microstructure of white matter is reflected in variousMRI contrasts. Transverse relaxation rates can be probed as a function of fibre-orientation with respect to the main magnetic field, while diffusion properties are probed as a function of fibre-orientation with respect to an encoding gradient. While the latter is easy to obtain by varying the orientation of the gradient, as the magnetic field is fixed, obtaining the former requires re-orienting the head. In this work we deployed a tiltable RF-coil to study T2and diffusional anisotropy of the brain white matter simultaneously in diffusion-T2 correlation experiments. C. M. W. Tan and E. Kleban share first authorship. C. M. W. Tax (B) · E. Kleban · M. Chamberland · D. K. Jones Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK e-mail: TaxC@cardiff.ac.uk E. Kleban e-mail: KlebanE@cardiff.ac.uk M. Chamberland e-mail: ChamberlandM@cardiff.ac.uk D. K. Jones e-mail: JonesD27@cardiff.ac.uk M. Baraković Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK e-mail: muhamed.barakovic@epfl.ch Signal Processing Laboratory 5, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland Translational Imaging in Neurology Basel, Department of Biomedical Engineering, University Hospital Basel, Basel, Switzerland © The Author(s) 2021 E. Özarslan et al. (eds.), Anisotropy Across Fields and Scales, Mathematics and Visualization, https://doi.org/10.1007/978-3-030-56215-1_12 247 248 C. M. W. Tax et al.