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2022.
Formulation and characterization of cationic nanoemulsions as carriers for microRNA
Endogenously expressed microRNAs (miRNAs) act as post-transcriptional regulators of gene expression in various (patho)physiological processes. miRNA dysregulation is frequently linked to the onset and progression of numerous diseases, hence miRNA-based therapy could be an effective strategy for treating or preventing genetic, immune, or metabolic disorders. Even though miR-27a has been identified as a promising candidate for miRNA mimic therapy of obesity, its use is restricted due to enzymatic degradation and low membrane permeability [1].