Metabolic Turnover of Biogenic Amines In Physiological Fluids : Diagnostic Significances
The term of biogenic amine is an umbrella term that encompasses all amines with an origin in biological processes. This review will be restricted to the biogenic amine abnormalities that affect the metabolism of the catecholamines and serotonin mostly in patients with phaeochromocytoma and carcinoid syndrome, and the inborn errors that primarily affect their metabolism. An idea is also developed that proposes that abnormalities of biogenic amine metabolism are far more common than is currently considered, and that the search for these problems may be appropriate in any neonate or children who presents with neurological problems of unknown origin. Correction of the abnormal neurochemical pattern could predict treatment efficacy. This review article holds the reference values and metabolic ratio of catecholamines, serotonin and their metabolites in the serum, cerebrospinal fluids and urine for healthy persons and values and metabolic ratio of catecholamines, serotonin and their metabolites in patients with phaeochromocytoma and carcinoids syndrome.