Izvorni Znanstveni Rad Original Scientific Paper the Antiresorptive Effect of Intracanal Application of Alendronate in Canine Model
Antiresorptivni učinak intrakanalne aplikacije alendronata na eksperimentalnom modeluIntroduction The most frequent therapy used on patients with avulsed teeth is the method of replantation.Clinical and histological studies have shown that the main factors that have impact on replanted teeth are: the length of the extra-alveolar period, storage condition and maturation of the root (1,2,3). When the avulsed tooth is immediately replanted or stored in a solution capable of preserving the peri-odontal fibers attached to the root, the chances of success in replantation increase considerably (4-7).Nev-ertheless, in the majority of cases, the avulsed teeth are left exposed to a dry environment or extraalveolar for a long period of time. Thus, the treatment of the root surface and endodontic therapy of the avulsed