Coal remains an important component of the electricity system of Bosnia and Herzegovina, while the country is simultaneously undergoing a gradual energy transition toward lower-carbon technologies. This study evaluates the quality of coal from major mining areas in Tuzla Canton using laboratory results for composite samples from Kreka, Đurđevik and Banovići. The principal indicators were total moisture, ash, combustible matter and lower heating value (LHV). Eight mining areas were compared using five analytical samples per area, giving 40 observations for the primary statistical analysis. An additional 15 observations from five Banovići separation products were evaluated separately. Marked differences were identified among mining areas. Mean LHV ranged from 7,836 kJ/kg at PK Dubrave to 19,794 kJ/kg at Jama Omazići. Lignite from the Kreka area had substantially higher mean total moisture than the analysed brown coals, while several brown-coal areas were constrained by high ash content. Across the 40 primary observations, LHV showed a moderate negative correlation with total moisture (r = -0.43) and with ash (r = -0.37). A multiple linear model using moisture and ash explained approximately 98.4% of the observed LHV variation, although the small number of samples and the compositional nature of the variables require cautious interpretation. The findings demonstrate that coal reserves alone are insufficient for evaluating the future role of coal: fuel quality, preparation efficiency, plant efficiency, emissions intensity, economic performance and regulatory conditions must be considered together. The results support a transition strategy that combines improved coal characterisation and combustion efficiency in the medium term with accelerated deployment of renewable generation, storage, grid modernisation and just-transition measures.

Aim: To identify clinical and inflammatory factors associated with adequate haemoglobin control among patients receiving maintenance haemodialysis and erythropoiesis-stimulating agent (ESA) therapy. Methods: This analytical cross-sectional study included 100 adults receiving maintenance haemodialysis. Among 80 patients receiving ESA therapy, adequate haemoglobin control was defined as haemoglobin ≥ 100 g/L and inadequate control as haemoglobin < 100 g/L at the cross-sectional assessment; 20 patients not receiving ESA therapy were described separately. Clinical characteristics and laboratory measurements, including C-reactive protein (CRP), were recorded. The erythropoietin resistance index (ERI) was calculated from weekly ESA dose, body weight, and haemoglobin concentration. Results: Eighty patients (80.0%) received ESA therapy, while 20 (20.0%) did not. Among ESA-treated patients, longer haemodialysis vintage was associated with higher odds of adequate haemoglobin control (OR = 1.02, 95% CI 1.01–1.04), whereas higher CRP was associated with lower odds (OR = 0.90, 95% CI 0.83–0.99). ERI was inversely associated with adequate control (OR = 0.004, 95% CI 0.001–0.066), although this finding is mathematically coupled to the haemoglobin-based outcome. The exploratory model was statistically significant (χ² = 45.4; p < 0.001). Conclusion: Longer haemodialysis vintage and lower CRP were associated with adequate haemoglobin control during ESA therapy. ERI findings require cautious interpretation because haemoglobin is included in the ERI denominator and was also used to define the outcome.

The excessive use of vaccines, antibiotics, and other preventive therapeutic agents in conventional broiler production has resulted in the frequent occurrence of antibiotic residues in edible tissues, posing risks to both animal and human health. These residues contribute to the global problem of antimicrobial resistance, highlighting the need for alternative approaches to poultry disease prevention. This study aimed to evaluate whether a comprehensive preventive programme encompassing biosecurity, hygiene, and an antibiotic-free prophylaxis regimen could eliminate the need for prophylactic antibiotic therapy, thereby enabling the production of broiler meat free of antibiotic residues. This approach was contrasted with the conventional production system, in which less rigorous preventive practices necessitate the prophylactic use of broad-spectrum antibiotics, ultimately resulting in detectable residues within the muscle and liver tissues of conventionally reared chickens. Ross 308 broilers were reared under field conditions. in. The control group was reared using conventional prophylactic protocols, including broad-spectrum antibiotics, vitamins, bio-stimulants, mineral supplements, and acidifiers via drinking water. The experimental group received no antibiotics; and instead were treated with hydro-soluble probiotic preparations containing vitamin C, lactose, fructose, and baker’s yeast, combined with continuous water disinfection throughout the fattening period. Microbiological analyses showed the presence of antibiotic residues in the soft tissues of conventionally reared broilers, while no residues were detected in the experimental group. Production performance indicators—mortality rate, vitality, final body weight, and overall cost—were similar to or superior to those in the antibiotic-free group, confirming that broiler meat production without antibiotics is both feasible and economically viable.

Oral cancer remains a major health issue worldwide. Oral Potentially Malignant Disorders (OPMDs) constitute a wide range of lesions and conditions found in the oral cavity with a known risk of developing into oral squamous cell carcinoma. Common OPMDs include leukoplakia, erythroplakia, oral submucous fibrosis, oral lichen planus, and proliferative verrucous leukoplakia. Timely, well-targeted biopsy, coupled with risk-adapted follow-up and multidisciplinary care is essential to reduce malignant progression and achieve optimal patient outcomes. To address the absence of a unified weighting scheme for clinical and pathological predictors of malignant transformation in OPMDs, we conducted a targeted expert survey within the COST action INTERCEPTOR Working Group 2 (clinician-researchers with formal expertise in OPMDs). History of previous head and neck cancer, OPMD type, multifocality of the lesion clinical appearance and lifestyle habits received the highest weights in the survey on clinical prognostic factors. Future research priorities include development and validation of predictive models integrating clinical, histological, and molecular variables.

Rats are opportunistic omnivores, consuming both plant- and animal-derived foods, and therefore represent a suitable animal model for investigating the potential adverse effects of heterogeneous diets on hematological and biochemical blood profiles. The study included 18 Wistar rats of both sexes, aged 1–2 months, randomly allocated into three groups of six animals each. For a period of seven weeks, Group H was fed bakery products, Group M received meat and meat products, while the control Group K was fed a conventional pelleted diet. Biochemical parameters were analyzed from peripheral blood samples collected from the experimental animals. Statistically significant differences (p < 0.05) were identified among the groups for CREA, UREA, PHOS, Ca, TP, ALB, GLOB, ALB/GLOB, CHOL, and LIPA. No significant differences were observed for the remaining parameters. The biochemical findings indicate impaired renal function in rats from the meat-fed group, as evidenced by elevated creatinine, urea, phosphorus, and lipase levels. In addition, reduced concentrations of serum proteins, particularly albumin, were observed across all experimental groups, suggesting inadequate protein synthesis resulting from insufficient intake of essential amino acids and micronutrients required for normal liver function.

Industrial hemp ( Cannabis sativa L.) shows strong potential for phytoremediation due to its deep root system and high biomass; however, its ability to accumulate heavy metals raises concerns regarding its medicinal use. The aim of the study was to determine and compare the presence of five metals (Cd, As, Pb, Zn, and Fe) in three different plant organs/tissues and in inflorescence extracts in order to assess their suitability for food or medicinal use. Zinc was included as an essential micronutrient for comparison with toxic metal accumulation. The results demonstrate that hemp grown on contaminated soils accumulates elevated levels of cadmium and lead, primarily in the roots, while metal transfer to inflorescences and extracts remains limited. Genetic differences among breeding lines had little effect on metal uptake, indicating that cultivation for food, dietary supplement, or medicinal purposes should be restricted to uncontaminated soils in order to minimise health risks to patients and consumers.

Cornelian cherry ( Cornus mas L . ), known for its strong antioxidant and antiproliferative activity, is rich in vitamin C, polyphenols, flavonoids, anthocyanins

Deep Learning (DL)-based channel estimation has shown high accuracy and low latency in terrestrial 5G NR, but Low Earth Orbit (LEO) Non-Terrestrial Networks (NTNs) introduce Doppler and synchronization impairments that may require NTN-specific architectures. We test whether High-Efficiency Learning-based channel Estimation using dual Neural Attention (HELENA), originally designed for terrestrial channels, remains effective after NTN retraining and suitable across high-performance and power-constrained inference platforms. Its unchanged architecture is trained on paired receiver-compensated (NTN-1) and residual-impaired (NTN-2) datasets and compared with eight terrestrial-origin models trained on the same NTN data and the NTN-specific MDELAN-SISO. HELENA achieves the lowest observed SNR-averaged NMSE among the DL estimators in both conditions, including 55.8-62.7% lower linear-scale NMSE than MDELAN-SISO. All DL models degrade in NTN-2, demonstrating the challenge posed by residual Doppler and its associated impairments. On an RTX PRO 4500, HELENA achieves 0.0595 ms 99th-percentile (P99) inference latency, 88.1% below the 0.5 ms budget, with lower energy than its closest attention-based competitors. On a 10 W Jetson Orin NX, it retains a favorable accuracy-energy trade-off, but no model meets the P99 budget. Thus, HELENA needs no NTN-specific redesign for the evaluated task, while embedded tail latency remains an open challenge.